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Anti-DLL4 Antibody (aa586-598) LS-C205004

Ordering

Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular DLL4 Antibodies

Anti-DLL4 Antibody (Internal) LS-C19035
Rabbit Polyclonal to Human DLL4
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-DLL4 Antibody (clone 4A11) LS-C169100
Mouse Monoclonal [clone 4A11] (IgG1) to Human DLL4
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human DLL4
Human, Monkey, Mouse, Rat, Bat, Bovine, Guinea pig, Horse, Pig, Rabbit
Western blot, ELISA
Unconjugated

Details

Human DLL4
Goat
Human, Monkey, Mouse, Rat, Bat, Bovine, Guinea pig, Horse, Pig, Rabbit (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Western blot (0.3 - 1 µg/ml)
  • ELISA (1:64000)

Specificity and Use

DLL4 antibody was raised against synthetic peptide KNTNQKKELEVDC from an internal region of human DLL4 (NP_061947.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Mouse, Rat, Ferret, Bovine, Bat, Elephant, Panda, Rabbit, Horse, Pig, Guinea pig (100%); Pufferfish (85%).
aa586-598
Human DLL4. Notch signaling
Peptide ELISA: antibody detection limit dilution 1:64000. Western blot: Approx 80-85kD bands observed in Human, Mouse and Rat Lung lysates (calculated MW of 74.6kD according to NP_061947.1). Recommended concentration: 0.3-1 ug/ml.

Packaging

Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About DLL4

Q9NR61 NM_019074 NP_061947.1

DLL4 Antibody, Delta-like 4 protein Antibody, Delta like 4 Antibody, Delta-like 4 (Drosophila) Antibody, Delta-like 4 homolog Antibody, Drosophila Delta homolog 4 Antibody, Notch ligand DLL4 Antibody, Delta 4 Antibody, Delta ligand 4 Antibody, Delta-like protein 4 Antibody, Delta4 Antibody, Hdelta2 Antibody, Notch ligand delta-2 Antibody

Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation is required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate.

Western blot

Western blot
DLL4 antibody (0.3 ug/ml) staining of Human (A), Mouse(B) and Rat (C) Lung lysates (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence
 

Requested From: United States
Date Requested: 12/3/2016

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