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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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DEF6 Antibody (aa500‑528) LS‑C167347
DEF6 antibody LS-C167347 is an unconjugated rabbit polyclonal antibody to human DEF6. Validated for WB.
Catalog
Size
Price
LS-C167347-400
400 µl
Unavailable

Popular DEF6 Products

DEF6 antibody (1 ug/ml) staining of Human Thymus lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse, Pig, Rabbit
Applications: Western blot, Peptide Enzyme-Linked Immunosorbent Assay
IHC of paraffin-embedded Human tonsil using anti-DEF6 mouse monoclonal antibody.
Species: Human, Monkey, Dog
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
IHC of paraffin-embedded Human tonsil using anti-DEF6 mouse monoclonal antibody.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
IHC of paraffin-embedded Human tonsil using anti-DEF6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
IHC of paraffin-embedded Human lymphoma tissue using anti-DEF6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Species: Human, Monkey, Mouse, Rat, Dog
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot

Product Description

DEF6 antibody LS-C167347 is an unconjugated rabbit polyclonal antibody to human DEF6. Validated for WB.
About DEF6
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and CDC42. Can regulate cell morphology in cooperation with activated RAC1. Plays a role in Th2 (T helper cells) development and/or activation, perhaps by interfering with ZAP70 signaling. Q9H4E7 NM_022047 NP_071330.3

DEF6 Antibody, DEF-6 Antibody, IBP Antibody, SLAT Antibody, SWAP70L Antibody, IRF4-binding protein Antibody


Specifications

Target
Human DEF6
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Mouse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
Blocking Peptide
LS-E4280 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C167347. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa500-528
Specificity
This DEF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 500-528 amino acids from the C-terminal region of human DEF6.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (0)


Customer Reviews (0)


Images


Western blot

DEF6 Antibody western blot of A375 cell line lysates (35 ug/lane). The DEF6 antibody detected the DEF6 protein (arrow).
DEF6 Antibody western blot of A375 cell line lysates (35 ug/lane). The DEF6 antibody detected the DEF6 protein (arrow).

Western blot

DEF6 Antibody western blot of A375 cell line lysates (35 ug/lane). The DEF6 antibody detected the DEF6 protein (arrow).
DEF6 Antibody western blot of A375 cell line lysates (35 ug/lane). The DEF6 antibody detected the DEF6 protein (arrow).

Western blot

DEF6 Antibody western blot of A375 cell line lysates (35 ug/lane). The DEF6 antibody detected the DEF6 protein (arrow).
DEF6 Antibody western blot of A375 cell line lysates (35 ug/lane). The DEF6 antibody detected the DEF6 protein (arrow).

Western blot

DEF6 Antibody western blot of A375 cell line lysates (35 ug/lane). The DEF6 antibody detected the DEF6 protein (arrow).
DEF6 Antibody western blot of A375 cell line lysates (35 ug/lane). The DEF6 antibody detected the DEF6 protein (arrow).


Requested From: 
Date Requested: 6/18/2018

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