Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
Specificity and Use
DDX / AKR1C3 antibody was raised against synthetic peptide located between aa97-146 of human AKR1C3 (P42330, NP_003730). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Monkey (100%); Gibbon, Pig (92%); Bovine, Guinea pig (84%).
LS-E22461 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C145932. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Lyophilized from PBS with 2% sucrose
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
AKR1C3 Antibody, 3-alpha-HSD type 2 Antibody, 17-beta-HSD 5 Antibody, 3-alpha-HSD type II, brain Antibody, DD3 Antibody, DDH1 Antibody, DDX Antibody, Dihydrodiol dehydrogenase 3 Antibody, Dihydrodiol dehydrogenase X Antibody, DD-3 Antibody, HA1753 Antibody, HAKRe Antibody, HAKRB Antibody, HSD17B5 Antibody, KIAA0119 Antibody, Kia0119 Antibody, Prostaglandin F synthase Antibody, PGFS Antibody, Truncated aldoketo reductase a Antibody, HluPGFS Antibody, Indanol dehydrogenase Antibody
DDX / AKR1C3 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2.