LSBio The Immunohistochemistry Antibody Company
Products
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA Kits
  • All ELISA Kits
  • Traditional ELISA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Phospho-Specific ELISA Kits
  • ELISA Development Kits
  • Chemiluminescent CLIA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Immunohistochemistry
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
Services
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question? CustomerSupport@LSBio.com
Resources
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Our Rewards Program
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Protocols
  • Secure Logins
  • Login to Our Secure FTP Site
  • Login to Our IHC Database
Distributors
Contact Us

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Quick Order ▾
View Cart

Anti-CYR61 Antibody (aa250-350) LS-C49074

Note: This antibody replaces LS-C64181

Ordering

Wt. Vol. Conc. Price
- 100 µl 1 mg/ml Unavailable

Most Popular CYR61 Antibodies

Anti-CYR61 Antibody (aa250-350) LS-C49074
Rabbit Polyclonal to Human CYR61
Human, Rat
ICC, Immunofluorescence, Western blot
Unconjugated
Western blot Image
Anti-CYR61 Antibody (aa168-242, clone 3H3) IHC-plus™ LS-B2959
Mouse Monoclonal [clone 3H3] (IgG1,k) to Human CYR61
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-CYR61 Antibody IHC-plus™ LS-B8746
Rabbit Polyclonal (IgG) to Mouse CYR61
Mouse, Human, Rat
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human CYR61
Human, Rat
ICC, Immunofluorescence, Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human CYR61
Rabbit
Human, Rat (tested or 100% immunogen sequence identity)
Mouse (at least 90% immunogen sequence identity)
Mouse, Rat
Polyclonal
Unconjugated. Also available conjugated with Biotin, DY650, DY488, DY550.
Immunoaffinity purified
Unmodified

Applications

  • ICC (1:50 - 1:100)
  • Immunofluorescence (1:50 - 1:100)
  • Western blot (1:200)
  • (applications tested for the base form of this product only)

  • IHC - Paraffin

Specificity and Use

CYR61 antibody was raised against a synthetic peptide made to the human CYR61 protein sequence (between residues 250-350). Percent identity by BLAST analysis: Rat (100%); Mouse (96%).
aa250-350
Human CYR61 protein.

Packaging

Tris-citrate / phosphate buffer [pH 7-8], 0.09% sodium azide.
+4°C, avoid freezing
For research use only.

About CYR61

O00622 NM_001554 NP_001545.2

CYR61 Antibody, GIG1 Antibody, IGFBP10 Antibody, Protein CYR61 Antibody, CCN family member 1 Antibody, CCN1 Antibody, IBP-10 Antibody, IGF-binding protein 10 Antibody, IGFBP-10 Antibody, Protein GIG1 Antibody

Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1.

Western blot

Western blot
Detection of cleaved CYR61 in MDA-MB-231 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: 
Date Requested: 3/27/2017

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2017 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy
Catalog Number