Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 1A3] (IgG2b) to Human CSF2 / GM-CSF
IHC - Paraffin, Western blot
Rat Monoclonal [clone MP1-22E9] (IgG2a,k) to Mouse CSF2 / GM-CSF
Western blot, Sandwich ELISA
Mouse CSF2 / GM-CSF
Mouse (tested or 100% immunogen sequence identity)
IgG2a,k Monoclonal [MP1-22E9]
Specificity and Use
CSF2 / GM-CSF antibody was raised against yeast-expressed recombinant mouse GM-CSF
Useful as a capture antibody in a sandwich ELISA for quantifying mouse GM-CSF protein levels. Should be paired with biotinylated MP1-31G6 antibody as the detection antibody, with purified recombinant mouse GM-CSF as the standard. Also useful in Western blot under reducing conditions.
Borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added.
CSF2 / GM-CSF is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13.