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CREB5 belongs to the CRE (cAMP response element)-binding protein family. Members of this family contain zinc-finger and bZIP DNA-binding domains. The encoded protein specifically binds to CRE as a homodimer or a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene Name: | cAMP responsive element binding protein 5 |
Synonyms: | CREB5, CRE-BPA, CREB-5, H_GS165L15.1, CREBPA |
Target Sequences: | NM_004904 NP_004895.2 Q02930 |
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