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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CPSF3 / CPSF Antibody (C‑Terminus) LS‑C31378
CPSF antibody LS-C31378 is an unconjugated rabbit polyclonal antibody to CPSF (CPSF3) from human, rat, monkey and other species. Validated for IHC and WB.
Catalog
Size
Price
LS-C31378-100
100 µg (1 mg/ml)
Unavailable

Popular CPSF3 / CPSF Products

A: Marker, B: Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Chicken, Xenopus, Zebrafish
Applications: Western blot
CPSF3 monoclonal antibody (M06), clone 1H8. Western blot of CPSF3 expression in Raw 264.7.
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Detection of Human and Mouse CPSF73 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma (left) and mouse teratoma (right). Antibody: Affinity purified rabbit anti-CPSF73 used at a dilution of 1:200 (1 ug/ml). Detection: DAB.
Species: Human, Mouse, Bovine, Dog, Horse, Rabbit
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Anti-CPSF3 / CPSF antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11044 dilution 1:100.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Immunofluorescence
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot

Product Description

CPSF antibody LS-C31378 is an unconjugated rabbit polyclonal antibody to CPSF (CPSF3) from human, rat, monkey and other species. Validated for IHC and WB.
About CPSF3 / CPSF
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Has endonuclease activity, and functions as mRNA 3'-end-processing endonuclease. Also involved in the histone 3'-end pre-mRNA processing. Q9UKF6 NM_016207 NP_057291.1

CPSF3 Antibody, CPSF 73 kDa subunit Antibody, CPSF-73 Antibody, CPSF73 Antibody, CPSF Antibody, YSH1 Antibody


Specifications

Target
Human CPSF3 / CPSF
Host
Rabbit
Reactivity
Human, Monkey, Rat, Rabbit (tested or 100% immunogen sequence identity)
Predicted
Mouse, Bat, Bovine, Dog, Guinea pig, Horse, Chicken (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Western blot (1.25 µg/ml)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
CPSF3 / CPSF antibody was raised against synthetic peptide from C-Terminus of human CPSF3 (Q9UKF6, NP_057291). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Marmoset, Rat (100%); Galago, Mouse, Panda, Dog, Bovine, Bat, Horse, Guinea pig, Turkey, Chicken (92%); Elephant, Rabbit, Platypus, Lizard (85%).
Epitope
C-Terminus
Specificity
Human CPSF3
Presentation
Lyophilized from PBS with 2% sucrose
Reconstitution
100 µl After adding water, will consist of PBS buffer with 2% sucrose
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

CPSF3 antibody LS-C31378 was used in IHC to stain formalin-fixed, paraffin-embedded human liver.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CPSF3 antibody LS-C31378 was used in IHC to stain formalin-fixed, paraffin-embedded human liver. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

B: Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
B: Jurkat Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

CPSF3 antibody LS-C31378 was used in IHC to stain formalin-fixed, paraffin-embedded human liver.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CPSF3 antibody LS-C31378 was used in IHC to stain formalin-fixed, paraffin-embedded human liver. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

B: Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
B: Jurkat Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

CPSF3 antibody LS-C31378 was used in IHC to stain formalin-fixed, paraffin-embedded human liver.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CPSF3 antibody LS-C31378 was used in IHC to stain formalin-fixed, paraffin-embedded human liver. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

B: Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
B: Jurkat Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

CPSF3 antibody LS-C31378 was used in IHC to stain formalin-fixed, paraffin-embedded human liver.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CPSF3 antibody LS-C31378 was used in IHC to stain formalin-fixed, paraffin-embedded human liver. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

B: Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
B: Jurkat Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/21/2018

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