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Anti-Complement C5 Antibody LS-C41851

Note: This antibody replaces LS-C79719, LS-C22318


Wt. Vol. Conc. Price
- 1000 µl - $345
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular Complement C5 Antibodies

Anti-Complement C5 Antibody LS-C79716
Mouse Monoclonal (IgG2a) to Human Complement C5
Western blot, ELISA
Anti-Complement C5 Antibody (clone 557) LS-C14521
Mouse Monoclonal [clone 557] (IgG2b) to Human Complement C5
Western blot, ELISA
Anti-Complement C5 Antibody (clone 12F3) LS-C22316
Mouse Monoclonal [clone 12F3] (IgG1,k) to Human Complement C5
Western blot, ELISA

100% Guaranteed 100% Guaranteed
Sheep Polyclonal (IgG) to Human Complement C5


Human Complement C5
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Ion exchange chromatography



Specificity and Use

Complement C5 antibody was raised against human C5, purified from plasma.
Recognizes complement component 5 (C5), a member of the complement system. The complement system consists of a tightly regulated network of proteins. Its activation leads to a sequential cascade of enzymatic reactions, resulting in opsonisation of the pathogens and their removal by phagocytes, as well as cell lysis. Three pathways have been described, the antibody-dependent pathway (classical pathway), the alternative pathway and the lectin activation pathway. The complement system plays a critical role in both innate and adaptive immune responses. It is also involved in tissue regeneration, tumor growth and some human pathologies. Complement component 5 is the initiator of the effector terminal phase of the complement system. C5 convertase cleaves C5 into C5a, a potent anaphylatoxin, and C5b, ultimately resulting in the formation of the multimeric membrane attack complex (MAC) together with the other components of the terminal pathway (C5b-C9). Gives a single arc when tested by immunoelectrophoresis (IEP) against human plasma. The identity has been confirmed by double diffusion against fresh human plasma and a known anti human C5.


Glycine buffered saline, pH 7.4, 0.09% sodium azide, 0.1% EACA, 0.01% benzamidine, 1 mM EDTA.
For research use only.

About Complement C5

P01031 NM_001735 NP_001726.2

C5 Antibody, Anaphylatoxin C5a analog Antibody, CPAMD4 Antibody, Complement C5 Antibody, Complement component 5 Antibody

Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled.Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process.

Requested From: United States
Date Requested: 10/28/2016

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