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Anti-Complement C3 / C3b Antibody (clone H11) LS-C11221


Wt. Vol. Conc. Price
50 µg 1 ml - $635
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular Complement C3 / C3b Antibodies

Anti-Complement C3 / C3b Antibody (clone H11) LS-C11221
Mouse Monoclonal [clone H11] (IgG1) to Human Complement C3 / C3b
IHC - Frozen, Western blot
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Anti-Complement C3 / C3b Antibody LS-C191523
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100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone H11] (IgG1) to Human Complement C3 / C3b
IHC - Frozen, Western blot


Human Complement C3 / C3b
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [H11]
Protein A purified


  • IHC - Frozen (1:10)
  • Western blot

Specificity and Use

Native human C3 / Complement C3.
Recognizes human C3b, part of the complement system. C3 is cleaved by C3-convertase creating C3a and C3b, which binds to the surface of pathogens leading to their destruction by phagocytic cells. Recognizes a determinant present on native (circulating) C3 and on the fragments C3b and C3c. The antibody is directed to a determinant present on the beta chain of the C3 molecule (Western blot). It does not react with the anaphylatoxin C3a or the fragment C3d and does not inhibit the hemolytic function of C3.


Lyophilized, PBS, 0.09% sodium azide, 0.5% BSA.
1 ml Distilled Water.
Store lyophilized at 4°C. Once reconstituted, aliquot and store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About Complement C3 / C3b

Complement C3b is the larger of two elements formed by the cleavage of complement component 3. C3b covalently bonds to microbial cell surfaces within an organism's body. This leads to the production of surface-bound C3-convertase and thus more C3b components. Bound C3b also aids in opsonization of the microbe by macrophages. Complement receptor 1 (CR1) on macrophages allows the engaging of C3b covered microbes. C3b also aids in the clearance of immune complexes (antigen-antibody).

Requested From: United States
Date Requested: 10/26/2016

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