Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone hCMV34] (IgG2a) to Cytomegalovirus CMV gB
IHC - Frozen, Immunofluorescence, ELISA
Cytomegalovirus CMV gB
Cytomegalovirus (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [hCMV34]
IHC - Frozen
Specificity and Use
CMV gB antibody was raised against native.
Detects cytomegalovirus glycoprotein B late cytoplasmic antigen. Cytomegalovirus is an enveloped double stranded DNA virus which in humans (HCMV) is commonly known as human herpesvirus 5 (HHV-5). Glycoprotein B (gB) is the main antigenic protein within the envelope of HCMV. It is required for HCMV mediated membrane fusion along with the gH / gL complex. The unprocessed precursor of HCMV gB is 906 amino acids in length, with a MW of approximately 100kD. Does not react with HSV, VZV or EBV. Reacts with MRC-5 infected cells, but not uninfected cells. Has been used successfully to demonstrate presence of CMV in infected cells by immunofluorescence on paraformaldehyde fixed cell cultures.
Immunohistology: Reactive only in acetone fixed CMV infected cells or frozen sections.