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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CHUK / IKKA / IKK Alpha Antibody (Met17) LS‑C176077
IKK Alpha antibody LS-C176077 is an unconjugated rabbit polyclonal antibody to IKK Alpha (CHUK / IKKA) from human, mouse and rat. Validated for IHC and WB.
Catalog
Size
Price
LS-C176077-100
100 µl
Unavailable

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Product Description

IKK Alpha antibody LS-C176077 is an unconjugated rabbit polyclonal antibody to IKK Alpha (CHUK / IKKA) from human, mouse and rat. Validated for IHC and WB.
About CHUK / IKKA / IKK Alpha
Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. O15111 NM_001278 NP_001269.3

CHUK Antibody, I-kappa-B kinase alpha Antibody, I-kappa-B kinase-alpha Antibody, Ikb kinase alpha Antibody, IKK-A Antibody, IKBKA Antibody, IKK1 Antibody, NFKBIKA Antibody, I-kappa-B kinase 1 Antibody, IkappaB kinase Antibody, IKK Alpha Antibody, IKK-alpha Antibody, IKKA Antibody, Transcription factor 16 Antibody, IkappaBalpha Kinase Antibody, IkB kinase alpha subunit Antibody, IKK-a kinase Antibody, Ikkalpha Antibody, TCF-16 Antibody, TCF16 Antibody


Specifications

Target
Human CHUK / IKKA / IKK Alpha
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide around Met17 of human CHUK / IKKA / IKK Alpha
Epitope
Met17
Specificity
Human CHUK / IKKA / IKK Alpha
Presentation
PBS, pH 7.2, 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

IHC of IKK- (M17) pAb in paraffin-embedded human colon carcinoma tissue.
IHC of IKK- (M17) pAb in paraffin-embedded human colon carcinoma tissue.

Western blot

Western blot of IKK- (M17) pAb in extracts from MDA-MB-435 cells treated with EGF.
Western blot of IKK- (M17) pAb in extracts from MDA-MB-435 cells treated with EGF.

Immunohistochemistry

IHC of IKK- (M17) pAb in paraffin-embedded human colon carcinoma tissue.
IHC of IKK- (M17) pAb in paraffin-embedded human colon carcinoma tissue.

Western blot

Western blot of IKK- (M17) pAb in extracts from MDA-MB-435 cells treated with EGF.
Western blot of IKK- (M17) pAb in extracts from MDA-MB-435 cells treated with EGF.

Immunohistochemistry

IHC of IKK- (M17) pAb in paraffin-embedded human colon carcinoma tissue.
IHC of IKK- (M17) pAb in paraffin-embedded human colon carcinoma tissue.

Western blot

Western blot of IKK- (M17) pAb in extracts from MDA-MB-435 cells treated with EGF.
Western blot of IKK- (M17) pAb in extracts from MDA-MB-435 cells treated with EGF.

Immunohistochemistry

IHC of IKK- (M17) pAb in paraffin-embedded human colon carcinoma tissue.
IHC of IKK- (M17) pAb in paraffin-embedded human colon carcinoma tissue.

Western blot

Western blot of IKK- (M17) pAb in extracts from MDA-MB-435 cells treated with EGF.
Western blot of IKK- (M17) pAb in extracts from MDA-MB-435 cells treated with EGF.


Requested From: 
Date Requested: 6/23/2018

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