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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CHUK / IKKA / IKK Alpha Antibody (aa557‑745) LS‑C15904
IKK Alpha antibody LS-C15904 is an unconjugated rabbit polyclonal antibody to human IKK Alpha (CHUK / IKKA). Validated for IP and WB.
Antibody
Catalog
Size
Price
LS-C15904-200
200 µg
$455

Popular CHUK / IKKA / IKK Alpha Products

Western blot of 30 ug of total cell lysate from Daudi cells with antibody at 1 ug/ml dilution.
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Anti-CHUK / IKK-Alpha antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2900 dilution 1:250.
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Product Description

IKK Alpha antibody LS-C15904 is an unconjugated rabbit polyclonal antibody to human IKK Alpha (CHUK / IKKA). Validated for IP and WB.

Specifications

Target
Human CHUK / IKKA / IKK Alpha
Synonyms
CHUK, I-kappa-B kinase alpha, I-kappa-B kinase-alpha, Ikb kinase alpha, IKK-A, IKBKA, IKK1, NFKBIKA, I-kappa-B kinase 1, IkappaB kinase, IKK Alpha, IKK-alpha, IKKA, Transcription factor 16, IkappaBalpha Kinase, IkB kinase alpha subunit, IKK-a kinase, Ikkalpha, TCF-16, TCF16
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1:2000)
  • Immunoprecipitation (1:500)
Immunogen
E. coli-expressed human IKKa fragment (aa557-745).
Epitope
aa557-745
Specificity
Reacts with human IKKa.
Usage
Suitable for use in Western Blot and Immunoprecipitation. Western Blot: 1:2000. Immunoprecipitation: 1:500.
Presentation
Lyophilized
Reconstitution
100 µl deionized water
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
About CHUK / IKKA / IKK Alpha
Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. O15111 NM_001278 NP_001269.3


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Requested From: United States
Date Requested: 10/16/2018

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