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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CDKN1B / p27 Kip1 Antibody LS‑C17115
P27 Kip1 antibody LS-C17115 is an unconjugated rabbit polyclonal antibody to p27 Kip1 (CDKN1B) from human, mouse and rat. Validated for IP and WB.
Antibody
Catalog
Size
Price
LS-C17115-100
100 µl
$530

Popular CDKN1B / p27 Kip1 Products

Anti-CDKN1B / p27 Kip1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5389 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Anti-CDKN1B / p27 Kip1 antibody IHC of human intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5740 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
IHC of p27 on FFPE Breast Adenocarcinoma tissue.
Species: Human
Applications: IHC, IHC - Paraffin, IHC - Frozen
Anti-CDKN1B / p27 Kip1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3943 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Anti-CDKN1B / p27 Kip1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1465 dilution 1:500.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot

Product Description

CDKN1B / p27 Kip1 Antibody for IP, WB/Western LS-C17115

Specifications

Target
Human CDKN1B / p27 Kip1
Synonyms
CDKN1B, KIP1, MEN1B, P27 Kip1, p27KIP1, MEN4, CDKN4
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
  • Immunoprecipitation (1:100)
Immunogen
Synthetic peptide derived from the sequence of human p27 (KLH coupled).
Specificity
Detects total levels of endogenous p27 protein. May recognize p57 Kip2. Species cross-reactivity: Mouse and rat.
Usage
Suitable for use in Western Blot and Immunoprecipitation. Western Blot: 1:1000. Immunoprecipitation: 1:100.
Presentation
10 mM HEPES, pH 7.5, 150 mM NaCl, 0.1 mg/ml BSA, 50% Glycerol, No preservatives added
Storage
Short term: -20°C; Long term: -20°C.
Restrictions
For research use only.
About CDKN1B / p27 Kip1
Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. P46527 NM_004064 NP_004055.1


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Requested From: United States
Date Requested: 10/15/2018

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