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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
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CDKN1B / p27 Kip1

cyclin-dependent kinase inhibitor 1B (p27, Kip1)

Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.

Gene Name: cyclin-dependent kinase inhibitor 1B (p27, Kip1)
Synonyms: CDKN1B, KIP1, MEN1B, P27 Kip1, p27KIP1, MEN4, CDKN4
Target Sequences: NM_004064 NP_004055.1 P46527

Publications (2)

1
Phosphorylation of p27Kip1 by Epstein-Barr virus protein kinase induces its degradation through SCFSkp2 ubiquitin ligase actions during viral lytic replication. Iwahori S, Murata T, Kudoh A, Sato Y, Nakayama S, Isomura H, Kanda T, Tsurumi T. The Journal of biological chemistry. 2009 284:18923-31. (WB) [PubMed:19451650] [PMC:PMC2707218]
2
Androgen Receptor Enhances p27 Degradation in Prostate Cancer Cells through Rapid and Selective TORC2 Activation. Fang Z, Zhang T, Dizeyi N, Chen S, Wang H, Swanson KD, Cai C, Balk SP, Yuan X. The Journal of biological chemistry. 2012 287:2090-8. [PubMed:22139837] [PMC:PMC3265888]

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Viewing 1-25 of 257 items
CDKN1B / p27 Kip1 Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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(1) Publication(s)
Rabbit Polyclonal to Human CDKN1B / p27 Kip1
Human
IHC-P, WB
Unconjugated
200µl   $425.00
CDKN1B / p27 Kip1 Antibody - Anti-CDKN1B / p27 Kip1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Mouse Monoclonal [clone 4B4-E6] (IgG1,k) to Human CDKN1B / p27 Kip1
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µg   0.5mg/ml   $545.00
CDKN1B / p27 Kip1 Antibody - Anti-CDKN1B / p27 Kip1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Goat Polyclonal to Human CDKN1B / p27 Kip1
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µg   0.5mg/ml   $425.00
CDKN1B / p27 Kip1 Antibody - Anti-CDKN1B / p27 Kip1 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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Rabbit Polyclonal (IgG) to Human CDKN1B / p27 Kip1
Mouse, Rat, Human
IHC-P, IP, WB
Unconjugated
250µl   $425.00
CDKN1B / p27 Kip1 Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Rabbit Polyclonal (IgG) to Human CDKN1B / p27 Kip1
Mouse, Rat, Human
IHC-P
Unconjugated
250µl   $485.00
CDKN1B / p27 Kip1 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Rabbit Polyclonal (IgG) to Mouse CDKN1B / p27 Kip1
Mouse, Rat, Human
IHC
Unconjugated
60µl   0.89mg/ml   $425.00
CDKN1B / p27 Kip1 Antibody - Western blot of Phospho-p27 (T187) antibody
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Rabbit Polyclonal (IgG) to Human CDKN1B / p27 Kip1
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
CDKN1B / p27 Kip1 Antibody - Western blot of Phospho-p27 (T198) antibody
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Rabbit Polyclonal (IgG) to Human CDKN1B / p27 Kip1
Human
ELISA, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
CDKN1B / p27 Kip1 Antibody - IHC of p27 on FFPE Breast Adenocarcinoma tissue.
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Mouse Monoclonal [clone SX53G8] (IgG1,k) to Human CDKN1B / p27 Kip1
Human
IHC, IHC-Fr, IHC-P
Unconjugated
0.1ml   $255.00; 0.5ml   $375.00; 1ml   $545.00
CDKN1B / p27 Kip1 Antibody - Formalin-fixed, paraffin-embedded human cervical cancer stained with p27 antibody (DCS-72.F6).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone DCS-72.F6] (IgG1,k) to Mouse CDKN1B / p27 Kip1
Mouse, Rat, Human, Monkey
Flo, IF, IHC, IHC-P, WB
Unconjugated
20µg   0.2mg/ml   $295.00; 100µg   0.2mg/ml   $465.00
CDKN1B / p27 Kip1 Antibody - Formalin-fixed, paraffin-embedded human cervical cancer stained with p27 antibody (DCS-72.F6).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone DCS-72.F6] (IgG1,k) to Mouse CDKN1B / p27 Kip1
Mouse, Rat, Human, Monkey
Flo, IF, IHC, IHC-P, WB
Unconjugated, Ready-to-Use
7ml   $465.00
CDKN1B / p27 Kip1 Antibody - Formalin-fixed, paraffin-embedded human cervical cancer stained with p27 antibody (DCS-72.F6).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone DCS-72.F6] (IgG1,k) to Mouse CDKN1B / p27 Kip1
Mouse, Rat, Human, Monkey
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free
100µg   1mg/ml   $465.00
CDKN1B / p27 Kip1 Antibody - Immunohistochemical analysis of p27 Kip1 (pT187) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX. w
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Rabbit Polyclonal to Human CDKN1B / p27 Kip1
Mouse, Dog, Bovine, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $265.00
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Mouse Monoclonal [clone DCS-72.F6] (IgG1,k) to Mouse CDKN1B / p27 Kip1
Mouse, Dog, Rat
Flo, IF, IP, WB
Biotin Conjugated
100µl   $335.00; 500µl   $740.00; 1000µl   $1,110.00
CDKN1B / p27 Kip1 Antibody - Immunohistochemical analysis of p27 Kip1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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Rabbit Polyclonal to Human CDKN1B / p27 Kip1
Mouse, Dog, Bovine, Human
IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $245.00
CDKN1B / p27 Kip1 Antibody - Formalin-fixed, paraffin-embedded human colon carcinoma stained with p27Kip1 antibody (KIP1/769).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone KIP1/769] (IgG1,k) to Human CDKN1B / p27 Kip1
Mouse, Rat, Human, Monkey
Flo, IF, IHC, IHC-P, WB
Unconjugated
20µg   0.2mg/ml   $295.00; 100µg   0.2mg/ml   $465.00
CDKN1B / p27 Kip1 Antibody - Formalin-fixed, paraffin-embedded human colon carcinoma stained with p27Kip1 antibody (KIP1/769).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone KIP1/769] (IgG1,k) to Human CDKN1B / p27 Kip1
Mouse, Rat, Human, Monkey
Flo, IF, IHC, IHC-P, WB
Unconjugated, Ready-to-Use
7ml   $465.00
CDKN1B / p27 Kip1 Antibody - Formalin-fixed, paraffin-embedded human colon carcinoma stained with p27Kip1 antibody (KIP1/769).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone KIP1/769] (IgG1,k) to Human CDKN1B / p27 Kip1
Mouse, Rat, Human, Monkey
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free
100µg   1mg/ml   $465.00
CDKN1B / p27 Kip1 Antibody - IHC testing of FFPE human prostate cancer and p27Kip1 antibody (clone KIP27-1).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone KIP27-1] (IgG1,k) to Human CDKN1B / p27 Kip1
Mouse, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20µg   0.2mg/ml   $295.00; 100µg   0.2mg/ml   $465.00
CDKN1B / p27 Kip1 Antibody - IHC testing of FFPE human prostate cancer and p27Kip1 antibody (clone KIP27-1).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone KIP27-1] (IgG1,k) to Human CDKN1B / p27 Kip1
Mouse, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free
100µg   1mg/ml   $465.00
CDKN1B / p27 Kip1 Antibody - IHC testing of FFPE human prostate cancer and p27Kip1 antibody (clone KIP27-1).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone KIP27-1] (IgG1,k) to Human CDKN1B / p27 Kip1
Mouse, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Ready-to-Use
7ml   $465.00
CDKN1B / p27 Kip1 Antibody - Western blot analysis of lysates from HeLa cells treated with EGF or IFN-α, using p27 Kip1 (Phospho-Thr187) Antibody. The lane on the left is blocked with the phospho peptide.
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Rabbit Polyclonal (IgG) to Human CDKN1B / p27 Kip1
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
CDKN1B / p27 Kip1 Antibody - Western blot analysis of lysates from HeLa cells, HepG2 cells and COLO cells, using p27 Kip1 (Phospho-Thr198) Antibody. The lane on the right is blocked with the phospho peptide.
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Rabbit Polyclonal (IgG) to Human CDKN1B / p27 Kip1
Human
Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
Select
Mouse Monoclonal (IgG1) to Mouse CDKN1B / p27 Kip1
Mouse, Dog, Rat, Human, Monkey
Flo, IF, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
100µg   $635.00
CDKN1B / p27 Kip1 Antibody - Formalin-fixed, paraffin-embedded human colon carcinoma stained with p27 antibody (DCS-72.F6 + KIP1/769).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone DCS-72.F6 + KIP1/769] (IgG) to Mouse CDKN1B / p27 Kip1
Mouse, Rat, Human, Monkey
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free
100µg   1mg/ml   $465.00

Viewing 1-25 of 257 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).