Mouse CDK4

Rabbit

Mouse, Human (tested or 100% immunogen sequence identity)

Rat, Bovine, Guinea pig, Hamster, Sheep (at least 90% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Immunoaffinity purified

Unmodified

Synthetic peptide from the C-Terminus of mouse Cdk4 (RISAFRALQHSYLHKEESDAE, aa283-303 of UniProt P30285). Percent identity by BLAST analysis: Mouse (100%); Rat, Hamster (95%); Sheep, Bovine, Guinea pig (90%); Human, Bat, Rabbit, Pig (81%).

aa283-303

Mouse CDK4

• Western blot (0.5 - 1 µg/ml)

Cyclin-dependent kinase-4 (CDK4) is a protein-serine kinase involved in the cell cycle. Human cell division is regulated primarily at the G1-to-S or the G2-to-M boundaries within the cell cycle. The complexes formed by CDK4 and the D-type cyclins are involved in the control of cell proliferation during the G1 phase. CDK4 is inhibited by p16, also known as cyclin-dependent kinase inhibitor-2. CDK4 is mapped to 12q14. CDK4 expression and activity are required for cytokine responsiveness in T cells.

Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.

Reconstitute in sterile distilled water.

Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P11802 NCBI: NM_000075 NP_000066.1