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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CDK3 Antibody (aa1‑238) LS‑C185680
CDK3 antibody LS-C185680 is an unconjugated rabbit polyclonal antibody to human CDK3. Validated for WB.
Catalog
Size
Price
LS-C185680-100
100 µl (1 mg/ml)
Unavailable

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Product Description

CDK3 antibody LS-C185680 is an unconjugated rabbit polyclonal antibody to human CDK3. Validated for WB.
About CDK3
Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Q00526 NM_001258 NP_001249.1

CDK3 Antibody, Cell division protein kinase 3 Antibody, Cell division kinase 3 Antibody, Cyclin-dependent kinase 3 Antibody


Specifications

Target
Human CDK3
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Bovine (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:500 - 1:3000)
Immunogen
CDK3 antibody was raised against recombinant fragment corresponding to a region within amino acids 1 and 238 of Cdk3 (SwissProt Q00526). Percent identity by BLAST analysis: Human (100%); Bovine (92%); Chicken (88%).
Epitope
aa1-238
Specificity
Human CDK3
Presentation
0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal
Storage
Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Sample (30 ug of whole cell lysate). A: Hep G2 . 10% SDS PAGE. Cdk3 antibody. CDK3 antibody diluted at 1:1000.
Sample (30 ug of whole cell lysate). A: Hep G2 . 10% SDS PAGE. Cdk3 antibody. CDK3 antibody diluted at 1:1000.

Western blot

Sample (30 ug of whole cell lysate). A: Hep G2 . 10% SDS PAGE. Cdk3 antibody. CDK3 antibody diluted at 1:1000.
Sample (30 ug of whole cell lysate). A: Hep G2 . 10% SDS PAGE. Cdk3 antibody. CDK3 antibody diluted at 1:1000.

Western blot

Sample (30 ug of whole cell lysate). A: Hep G2 . 10% SDS PAGE. Cdk3 antibody. CDK3 antibody diluted at 1:1000.
Sample (30 ug of whole cell lysate). A: Hep G2 . 10% SDS PAGE. Cdk3 antibody. CDK3 antibody diluted at 1:1000.

Western blot

Sample (30 ug of whole cell lysate). A: Hep G2 . 10% SDS PAGE. Cdk3 antibody. CDK3 antibody diluted at 1:1000.
Sample (30 ug of whole cell lysate). A: Hep G2 . 10% SDS PAGE. Cdk3 antibody. CDK3 antibody diluted at 1:1000.


Requested From: 
Date Requested: 6/19/2018

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