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Anti-CD45 / LCA Antibody (clone MAC323) LS-C188139

Ordering

Wt. Vol. Conc. Price
1000 µg - 1 mg/ml $560
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular CD45 / LCA Antibodies

Anti-CD45 / LCA Antibody (PE) LS-C127700
Mouse Monoclonal (IgG1) to Sheep CD45 / LCA
Sheep, Bovine, Goat
Flow Cytometry
PE Conjugated
Anti-CD45 / LCA Antibody (Internal) IHC-plus™ LS-A9435
Rabbit Polyclonal to Human CD45 / LCA
Human
IHC - Paraffin
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone MAC323] (IgG2a) to Pig CD45 / LCA
Pig
IHC - Paraffin, IHC - Frozen, Immunoprecipitation, Flow Cytometry
Unconjugated

Details

Pig CD45 / LCA
Mouse
Pig (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [MAC323]
Unconjugated
Ion exchange chromatography
Unmodified

Applications

  • IHC - Paraffin (1:10)
  • IHC - Frozen (1:10)
  • Immunoprecipitation
  • Flow Cytometry

Specificity and Use

CD45 / LCA antibody was raised against porcine PBL.
Recognizes an allotypic determinant of porcine CD45, also known as Leucocyte common antigen (LCA). The antibody has been shown to recognize pigs of strains Large White and German Landrace. Another antibody K252.1E4, recognizes a monomorphic determinant on porcine CD45. The latter, used in conjunction with MAC323 it is noted that MCA323 stains a subset of animals that stain with K252.1E4 indicating loss of the epitope in MCA323+ve animals rather than the loss of CD45 antigen. Cross-breeding studies in positive vs. negative animals indicate that the MAC323 gene is inherited in a simple Mendelian autosomally dominant pattern (Binns et al. 1995).

Packaging

PBS, 0.09% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About CD45 / LCA

P08575 NM_002838 NP_002829.3

PTPRC Antibody, B220 Antibody, CD45R Antibody, CD45 Antibody, gp180 Antibody, Leukocyte common antigen Antibody, L-CA Antibody, Leucocyte common antigen Antibody, LY5 Antibody, T200 Antibody, T200 glycoprotein Antibody, T200 leukocyte common antigen Antibody, CD45 antigen Antibody, LCA Antibody

CD45 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP.

Requested From: United States
Date Requested: 12/4/2016

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