Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis.
CD44 antibody immunohistochemistry of formalin-fixed and paraffin-embedded human esophagus carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
CD44 antibody confocal immunofluorescent analysis with HeLa cell. 0.01 mg/ml primary antibody was followed by PE-conjugated goat anti-mouse lgG (whole molecule). PE emits red fluorescence. DAPI was used to stain the cell nuclear (blue).
CD44 antibody western blot of HeLa cell line lysates (35 ug/lane). The CD44 antibody detected the CD44 protein (arrow).
CD44 Antibody flow cytometry of HeLa cells (right histogram) compared to a negative control cell (left histogram). PE-conjugated goat-anti-mouse secondary antibodies were used for the analysis.