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The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms.
Gene Name: | CD37 molecule |
Family/Subfamily: | Tetraspan , not assigned-Tetraspan |
Synonyms: | CD37, CD37 antigen, CD37 molecule, Leukocyte surface antigen CD37, gp52-40, TSPAN26, Leukocyte antigen CD37, Tetraspanin-26, Tspan-26 |
Target Sequences: | NM_001774 NP_001765.1 P11049 |
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