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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CD37 Antibody (clone IPO-24) LS-C391249

CD37 antibody LS-C391249 is an unconjugated mouse monoclonal antibody to human CD37. Validated for Flow and IF.
Catalog
Size
Price
LS-C391249-20
20 µg
$295
LS-C391249-100
100 µg
$465
Description
CD37 antibody LS-C391249 is an unconjugated mouse monoclonal antibody to human CD37. Validated for Flow and IF.
Target
Human CD37
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2b,k Monoclonal
Clone
IPO-24
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified. Also available Azide-free.
Applications
  • Immunofluorescence (0.5 - 1 µg/ml)
  • Flow Cytometry (0.5 - 1 µg/10E6 cells)
  • (applications tested for the base form of this product only)
Immunogen
CD37 antibody was raised against spleen cells from a patient with hairy cell leukemia were used as the immunogen for the CD37 antibody.
Specificity
Human CD37
Usage
Recognizes a protein of 33-55kDa, identified as CD37 (Workshop V. Code CD37.7). CD37 is strongly expressed on normal and neoplastic mature (sIg+) B-lymphocytes. In B-cell ontogeny, CD37 appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present, at low densities, on resting and activated T cells, neutrophils, monocytes, and some myelomonocytic leukemia cells. It is absent from platelets, erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins, including CD9, CD53, CD63, CD81, and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin'' lymphoma (B-NHL). Optimal dilution of the CD37 antibody should be determined by the researcher.
Presentation
0.01% BSA, 0.05% sodium azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only.
About CD37
P11049 NM_001774 NP_001765.1

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Requested From: United States
Date Requested: 2/17/2019
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