Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Protein A purified
Specificity and Use
CD121b / IL1R2 antibody was raised against purified, insect cell line Sf21-derived, recombinant human IL-1R II (aa14-343; Accession # P27930).
Recognizes human IL-1 RII.
Suitable for use in Flow cytometry: 10 ul labels 1-2.5 x 10^5 cells. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Saline, 0.5% BSA, 0.1% sodium azide
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. CFS conjugates are sensitive to light.
IL1R2 Antibody, CD121b Antibody, CD121b antigen Antibody, CDw121b Antibody, IL-1RT-2 Antibody, IL1R2c Antibody, Interleukin-1 receptor beta Antibody, Interleukin-1 receptor type II Antibody, IL-1R-beta Antibody, Antigen CDw121b Antibody, IL-1 type II receptor Antibody, IL-1R-2 Antibody, IL-1RT2 Antibody, IL1RB Antibody, Interleukin-1 receptor type 2 Antibody
Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN.