Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone R6G9] (IgG1) to Mouse CCL5 / RANTES
Mouse CCL5 / RANTES
Mouse (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [R6G9]
Specificity and Use
CCL5 / RANTES antibody was raised against mouse CCL5
This R6G9 antibody has been tested by immunoblot on lysates of LPS-activated Raw 264.7 cells. This can be used at less than or equal to 2 ug/ml. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
CCL5 Antibody, Chemokine (C-C motif) ligand 5 Antibody, D17S136E Antibody, EoCP Antibody, T-cell specific protein p288 Antibody, SCYA5 Antibody, SISd Antibody, T cell-specific protein P228 Antibody, Beta-chemokine RANTES Antibody, C-C motif chemokine 5 Antibody, RANTES Antibody, SIS-delta Antibody, Small-inducible cytokine A5 Antibody, T-cell-specific protein RANTES Antibody, TCP228 Antibody
Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).
Western Blot with anti-mouse CCL5/RANTES (clone R6G9). Raw 264.7 cells were treated with Brefeldin A (lane 1) or LPS and Brefeldin A (lane 2) for 16 hours prior to lysis, SDS-PAGE and immunoblot with R6G9.