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Anti-CAV1 / Caveolin 1 Antibody (aa73-84) IHC-plus™ LS-B192

Note: This antibody replaces LS-C20137, LS-C78001
Catalog Size Price
LS-B192-50 50 µg (0.5 mg/ml) Unavailable

Most Popular CAV1 / Caveolin 1 Antibodies

Anti-CAV1 / Caveolin 1 Antibody (N-Terminus) IHC-plus™ LS-A2869
Rabbit Polyclonal to Human CAV1 / Caveolin 1
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Sheep
IHC, IHC - Paraffin
Unconjugated
Anti-CAV1 / Caveolin antibody LS-A2869 IHC of human respiratory epithelium, bronchial smooth muscle, and alveoli. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CAV1 / Caveolin 1 Antibody (N-Terminus) IHC-plus™ LS-A2870
Rabbit Polyclonal to Human CAV1 / Caveolin 1
Human, Monkey
IHC, IHC - Paraffin
Unconjugated
Anti-CAV1 / Caveolin antibody LS-A2870 IHC of human respiratory epithelium and alveoli. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CAV1 / Caveolin 1 Antibody (clone 7C8) IHC-plus™ LS-B150
Mouse Monoclonal [clone 7C8] (IgG2b) to Human CAV1 / Caveolin 1
Human, Mouse, Rat, Sheep
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry
Unconjugated
Anti-CAV1 / Caveolin antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B150 concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-CAV1 / Caveolin 1 Antibody (aa73-84) IHC-plus™ LS-B192
Goat Polyclonal to Human CAV1 / Caveolin 1
Human, Monkey
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Unconjugated
Anti-CAV1 / Caveolin antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B192 concentration 5 ug/ml.
Anti-CAV1 / Caveolin 1 Antibody IHC-plus™ LS-B2209
Mouse Monoclonal (IgG1) to Chicken CAV1 / Caveolin 1
Chicken, Human
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation
Unconjugated
Anti-CAV1 / Caveolin antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2209 concentration 5 ug/ml.

100% Guaranteed Publications (1)
Goat Polyclonal to Human CAV1 / Caveolin 1
Human, Monkey
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Unconjugated

Details

Human CAV1 / Caveolin 1
Goat
Human, Monkey (tested or 100% immunogen sequence identity)
Guinea pig (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC
  • IHC - Paraffin (2.5 µg/ml)
  • Western blot (0.3 - 1 µg/ml)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:32000)

Specificity and Use

Synthetic peptide C-DELSEKQVYDAH from an internal region of human CAV1 / Caveolin (NP_001744.2). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Baboon, Monkey, Marmoset (100%); Orangutan, Guinea pig (92%); Mouse, Rat, Dog, Bat, Hamster, Rabbit, Horse (83%).
LS-E25900 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B192. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa73-84
Human CAV1 / Caveolin. No cross-reactivity expected to Caveolin 2 and Caveolin 3
Immunohistochemistry: LS-B192 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B192 was determined to be 2.5 ug/ml.

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

Publications (1)

1
A Frame-Shift Mutation in CAV1 Is Associated with a Severe Neonatal Progeroid and Lipodystrophy Syndrome. Schrauwen I, Szelinger S, Siniard AL, Kurdoglu A, Corneveaux JJ, Malenica I, Richholt R, Van Camp G, De Both M, Swaminathan S, Turk M, Ramsey K, Craig DW, Narayanan V, Huentelman MJ. PloS one. 2015 10:e0131797. (WB; Human) [Full Text Article] [PubMed:26176221] [PMC:PMC4503302]

About CAV1 / Caveolin 1

Q03135 NM_001753 NP_001744.2

CAV1 Antibody, Caveolin-1 Antibody, CGL3 Antibody, CAV Antibody, MSTP085 Antibody, VIP21 Antibody, BSCL3 Antibody

The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade.

Immunohistochemistry

Anti-CAV1 / Caveolin antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B192 concentration 5 ug/ml.
Anti-CAV1 / Caveolin antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B192 concentration 5 ug/ml.

Requested From: 
Date Requested: 5/25/2018

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