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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CASR/Calcium Sensing Receptor Antibody (aa854‑903) LS‑C117834
Calcium Sensing Receptor antibody LS-C117834 is an unconjugated rabbit polyclonal antibody to Calcium Sensing Receptor (CASR) from human, mouse and rat. Validated for IHC, Peptide-ELISA and WB. Cited in 1 publication.
Catalog
Size
Price
LS-C117834-50
50 µl
Unavailable
LS-C117834-100
100 µl
Unavailable

Popular CASR/Calcium Sensing Receptor Products

Anti-CASR/Calcium Sensing Receptor antibody IHC of human Thyroid, Medullary Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken
Applications: IHC, IHC - Paraffin
Anti-Calcium Sensing Receptor antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B78 concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse, Rat, Rabbit
Applications: IHC, IHC - Paraffin, IHC - Frozen, ICC, Western blot, Immunoprecipitation, Flow Cytometry, Radioimmunoassay
Anti-FIH / CASR antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7687 dilution 5 ug/ml.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken
Applications: IHC, IHC - Paraffin, IHC - Frozen, Western blot

Product Description

Calcium Sensing Receptor antibody LS-C117834 is an unconjugated rabbit polyclonal antibody to Calcium Sensing Receptor (CASR) from human, mouse and rat. Validated for IHC, Peptide-ELISA and WB. Cited in 1 publication.
About CASR/Calcium Sensing Receptor
CASR, a Calcium-Sensing Receptor, functions as a sensor in parathyroid and kidney to determine extracellular calcium concentration and to maintain calcium homeostasis. This receptor regulates both secretion of parathyroid hormone and excretion of urinary calcium. Mutations that inactivate CASR cause familial hypocalciuric hypercalcemia, which is also correlated with hyperparathyroidism. On the other hand, mutations that activate CASR cause autosomal dominant hypocalcemia. Hjalm et al. P41180 NM_000388 NP_000379.2

CASR Antibody, Ca sensing receptor Antibody, Ca2+ sensing receptor Antibody, Calcium-sensing receptor Antibody, FIH Antibody, EIG8 Antibody, GPRC2A Antibody, HHC Antibody, HHC1 Antibody, Hypocalciuric hypercalcemia 1 Antibody, PCAR1 Antibody, NSHPT Antibody, CAR Antibody, FHH Antibody


Specifications

Target
Human CASR/Calcium Sensing Receptor
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Western blot (1:500 - 1:1000)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:5000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide from human Calcium Sensing Receptor (aa854-903).
Epitope
aa854-903
Specificity
Calcium Sensing Receptor (Ab-888) Antibody detects endogenous levels of total Calcium Sensing Receptor protein.
Presentation
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Storage
Store at -20°C for up to 1 year.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (1)

1
Comparative expression of the extracellular calcium-sensing receptor in the mouse, rat, and human kidney. Graca JA, Schepelmann M, Brennan SC, Reens J, Chang W, Yan P, Toka H, Riccardi D, Price SA. American journal of physiology. Renal physiology. 2016 310:F518-33. (WB; Human) [Full Text Article] [PubMed:26661650] [PMC:PMC5005276]

Customer Reviews (0)


Images


Immunohistochemistry

IHC of paraffin-embedded human brain tissue, using Calcium Sensing Receptor (Ab-888) Antibody. The picture on the right is treated with the synthesized peptide.
IHC of paraffin-embedded human brain tissue, using Calcium Sensing Receptor (Ab-888) Antibody. The picture on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from LOVO cells, using Calcium Sensing Receptor (Ab-888) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from LOVO cells, using Calcium Sensing Receptor (Ab-888) Antibody. The lane on the right is treated with the synthesized peptide.

Immunohistochemistry

IHC of paraffin-embedded human brain tissue, using Calcium Sensing Receptor (Ab-888) Antibody. The picture on the right is treated with the synthesized peptide.
IHC of paraffin-embedded human brain tissue, using Calcium Sensing Receptor (Ab-888) Antibody. The picture on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from LOVO cells, using Calcium Sensing Receptor (Ab-888) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from LOVO cells, using Calcium Sensing Receptor (Ab-888) Antibody. The lane on the right is treated with the synthesized peptide.

Immunohistochemistry

IHC of paraffin-embedded human brain tissue, using Calcium Sensing Receptor (Ab-888) Antibody. The picture on the right is treated with the synthesized peptide.
IHC of paraffin-embedded human brain tissue, using Calcium Sensing Receptor (Ab-888) Antibody. The picture on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from LOVO cells, using Calcium Sensing Receptor (Ab-888) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from LOVO cells, using Calcium Sensing Receptor (Ab-888) Antibody. The lane on the right is treated with the synthesized peptide.

Immunohistochemistry

IHC of paraffin-embedded human brain tissue, using Calcium Sensing Receptor (Ab-888) Antibody. The picture on the right is treated with the synthesized peptide.
IHC of paraffin-embedded human brain tissue, using Calcium Sensing Receptor (Ab-888) Antibody. The picture on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from LOVO cells, using Calcium Sensing Receptor (Ab-888) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from LOVO cells, using Calcium Sensing Receptor (Ab-888) Antibody. The lane on the right is treated with the synthesized peptide.


Requested From: 
Date Requested: 6/24/2018

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