Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal (IgG) to Human CASP4 / Caspase 4
IHC - Paraffin, Western blot
Human CASP4 / Caspase 4
Human, Mouse (tested or 100% immunogen sequence identity)
IHC - Paraffin (2 µg/ml)
Western blot (1 µg/ml)
Specificity and Use
CASP4 / Caspase 4 antibody was raised against synthetic peptide corresponding to a 16aa peptide from human Caspase-4 amino terminus.
Recognizes human CASPASE-4 (N-TERMINAL). Species cross-reactivity: mouse.
Suitable for use in Immunohistochemistry (paraffin) and Western Blot. Immunohistochemistry (paraffin): 2 ug/ml. Western Blot: 1 ug/ml.
PBS, 0.02% sodium azide
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C
Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1b and IL-18.