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Anti-CA2 / Carbonic Anhydrase II Antibody LS-C42675

Ordering

Wt. Vol. Conc. Price
- 1000 µl - $415
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Most Popular CA2 / Carbonic Anhydrase II Antibodies

Anti-CA2 / Carbonic Anhydrase II Antibody IHC-plus™ LS-B692
Rabbit Polyclonal to Human CA2 / Carbonic Anhydrase II
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-CA2 / Carbonic Anhydrase II Antibody IHC-plus™ LS-B1439
Rabbit Polyclonal to Bovine CA2 / Carbonic Anhydrase II
Bovine, Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Sheep Polyclonal (IgG) to Human CA2 / Carbonic Anhydrase II
Human
Western blot, Immunodiffusion
Unconjugated

Details

Human CA2 / Carbonic Anhydrase II
Sheep
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Purified
Unmodified

Applications

  • Western blot (1:1000)
  • Immunodiffusion

Specificity and Use

CA2 / Carbonic Anhydrase II antibody was raised against purified human carbonic anhydrase II (CAII) prepared from erythrocytes.
Recognizes human carbonic anhydrase II, also known as Carbonate dehydratase II or Carbonic anhydrase C. Carbonic anhydrase II is a 259 amino acid ~30 kD enzyme essential for bone resorption and osteoclast differrentiation. Mutations in the CA2 gene has been identified as the cause of Osteopetrosis, autosomal recessive 3, a rare disease characterized by particularly dense bone, cerebral calcification and renal tubular acidisis. Product identity is confirmed by double diffusion vs. human CAII. No reactivity is seen in immunodiffusion against CAI.

Packaging

Glycine buffered saline, pH 7.4, 0.09% sodium azide, 0.1% EACA, 1 mM EDTA, 0.01% benzamidine.
For research use only.

About CA2 / Carbonic Anhydrase II

P00918 NM_000067 NP_000058.1

CA2 Antibody, CA-II Antibody, CAII Antibody, CAC Antibody, Car2 Antibody, Carbonate dehydratase II Antibody, Carbonic anhydrase C Antibody, Carbonic anhydrase II Antibody, Carbonic dehydratase Antibody, Carbonic anhydrase 2 Antibody, Carbonic anhydrase B Antibody

Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6.

Requested From: United States
Date Requested: 12/5/2016

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