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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BECN1 / Beclin‑1 Antibody (clone 4H10, DY550) LS‑C142415
Beclin-1 antibody LS-C142415 is a DY550-conjugated mouse monoclonal antibody to human Beclin-1 (BECN1). Validated for IHC and WB.
Catalog
Size
Price
LS-C142415-100
100 µl
Unavailable

Popular BECN1 / Beclin-1 Products

Anti-BECN1 / Beclin-1 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3202 concentration 5 ug/ml.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, ICC, Western blot, ELISA
Anti-BECN1 / Beclin-1 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3203 concentration 5 ug/ml.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Anti-BECN1 / Beclin-1 antibody IHC of human skin, epidermis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7113 dilution 1:50.
Species: Human
Applications: IHC, IHC - Paraffin, ICC, Western blot, Immunoprecipitation
IHC of paraffin-embedded Human liver tissue using anti-BECN1 mouse monoclonal antibody.
Species: Human, Rat, Dog
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Antibody
Species: Human, Mouse
Applications: IHC, Western blot, Flow Cytometry, ELISA

Product Description

Beclin-1 antibody LS-C142415 is a DY550-conjugated mouse monoclonal antibody to human Beclin-1 (BECN1). Validated for IHC and WB.
About BECN1 / Beclin-1
Beclin 1 is a coiled coil protein that interacts with prototypic cellular antiapoptotic gene Bcl2. Beclin 1 is widely expressed with highest levels reported in skeletal muscle. Three alternativaly spliced isoforms have been identified. Allelic deletion of beclin 1 results in a wide variety of cancers including breast cancer. Q14457 NM_003766 NP_003757.1

BECN1 Antibody, ATG6 Antibody, Beclin 1 Antibody, Beclin 1, autophagy related Antibody, Beclin1 Antibody, GT197 Antibody, Protein GT197 Antibody, VPS30 Antibody, Beclin-1 Antibody


Specifications

Target
Human BECN1 / Beclin-1
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey, Mouse, Chicken (at least 90% immunogen sequence identity)
Clonality
IgG1,k Monoclonal [4H10]
Conjugations
DyLight 550. Also available Unconjugated or conjugated with Biotin, DY650, DY488.
Purification
Purified IgG
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:50 - 1:100)
  • Western blot (2 µg/ml)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Full length human Beclin 1 protein [Swiss-Prot# Q14457]. Percent identity by BLAST analysis: Monkey (99%); Mouse (98%); Porcine (97%); Chicken (91%).
Specificity
Beclin 1 (4H10).
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
50 mM sodium borate
Storage
Store at 4°C. Do not freeze.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Staining of Beclin 1 in mouse lung.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Staining of Beclin 1 in mouse lung. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

Staining of Beclin 1 in mouse lung.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Staining of Beclin 1 in mouse lung. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

Staining of Beclin 1 in mouse lung.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Staining of Beclin 1 in mouse lung. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

Staining of Beclin 1 in mouse lung.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Staining of Beclin 1 in mouse lung. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/20/2018

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