Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 2D1] (IgG1) to Human BCL2L1 / BCL-XL
IHC - Paraffin, Western blot
Rabbit Polyclonal to Human BCL2L1 / BCL-XL
Human BCL2L1 / BCL-XL
Human (tested or 100% immunogen sequence identity)
Western blot (1:1000)
Specificity and Use
BCL2L1 / BCL-XL antibody was raised against the antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human Bcl-xL that contains serine 62. The sequence is conserved in mouse and rat.
The antibody reacts to Human Bcl-xL. Mouse and rat Bcl-xl. Species cross-reactivity: Human.
Suitable for use in Western Blot. Western Blot: 1:1000.
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane.