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BCL2L1 / BCL-XL

BCL2-like 1

Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.Isoform Bcl-X(L) also regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP availability from mitochondria through regulation of mitochondrial membrane ATP synthase F1F0 activity and regulates endocytic vesicle retrieval in hippocampal neurons through association with DMN1L and stimulation of its GTPase activity in synaptic vesicles.Isoform Bcl-X(S) promotes apoptosis.

Gene Name: BCL2-like 1
Family/Subfamily: Apoptosis
Synonyms: BCL2L1, Apoptosis regulator Bcl-X, Bcl-xL, BCL-XL/S, BCLXS, Bcl-2-like protein 1, BCL2-like 1, BCL2L, Bcl-X, Bcl-xS, BCLXL, PPP1R52, Bcl2-L-1, BCLX
Target Sequences: NM_001191 NP_001182.1 Q07817

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Products
Antibodies (180)
Primary (180)
BCL2L1 / BCL-XL (180)
Human (149)
Mouse (93)
Rat (92)
Bat (21)
Bovine (28)
Cat (1)
Chimpanzee (12)
Dog (35)
Gerbil (3)
Gibbon (9)
Hamster (27)
Horse (28)
Monkey (13)
Pig (30)
Rabbit (24)
Sheep (26)
IHC (87)
IHC-Fr (6)
IHC-P (43)
WB (157)
Flo (32)
ELISA (37)
ICC (8)
IF (44)
IP (28)
Peptide-ELISA (5)
rabbit (129)
mouse (50)
sheep (1)
Product Group
IHCPlus (5)
IgG (76)
IgG1 (3)
IgG1,k (1)
IgG2a (25)
IgG2a,k (3)
IgG3 (8)
monoclonal mc (50)
polyclonal pc (130)
2C11C2 (1)
2H12 (9)
3E2-2A5 (1)
7B2.5 (3)
7D9 (2)
804CT19.1.4 (1)
BX006 (3)
BX006 + 2H12 (3)
G1/G1-4 (1)
OTI2D1 (2)
OTI4A9 (2)
SPM165 (2)
SPM337 (2)
AP Conjugated (1)
APC (4)
APC Conjugated (5)
Azide-free (7)
Biotin Conjugated (12)
BSA-free (5)
Carrier-free (2)
Cy3 Conjugated (4)
Cy7 Conjugated (4)
DY488 Conjugated (1)
DY550 Conjugated (1)
FITC Conjugated (11)
HRP Conjugated (9)
Magnetic beads Conjugated (1)
PE Conjugated (6)
Preservative Free (1)
Ready-to-Use (3)
RPE Conjugated (1)
Sepharose Conjugated (1)
Unconjugated (123)
aa2-212 (32)
N-Terminus (15)
aa3-14 (14)
pSer62 (8)
Internal (6)
aa1-209 (5)
pThr47 (5)
pThr115 (3)
30-110 aa (2)
40-120 aa (2)
50-130 aa (2)
aa46-66 (2)
Ab-115 (1)
Asp61 (1)
C-Terminus (1)
Ser43 (1)
Ser56 (1)
aa 3-14 (1)
aa1-208 (1)
aa1-212 (1)
aa1-50 (1)
aa120-130 (1)
aa13-62 (1)
aa195-229 (1)
aa61-79 (1)
aa81-130 (1)
p47 (1)
p62 (1)
No (180)
BCL2L1 / BCL-XL Antibody - IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-BCL2L1 mouse monoclonal antibody.
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BCL2L1 / BCL-XL Mouse anti-Human Monoclonal (OTI2D1) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$409
BCL2L1 / BCL-XL Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal (aa1-208) Antibody
Mouse, Rat, Human
ICC, IF, IHC-P, IP, WB
Unconjugated
50 µl/$460
BCL2L1 / BCL-XL Antibody - Bcl-X antibody immunohistochemistry.  This image was taken for the unmodified form of this product. Other forms have not been tested.
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BCL2L1 / BCL-XL Mouse anti-Human Monoclonal (BX006) Antibody
Mouse, Dog, Sheep, Bovine, Rat, Hamster, Pig, Horse, Chimpanzee, Human, Monkey
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated
20 µg/$354; 100 µg/$550
BCL2L1 / BCL-XL Antibody - Bcl-X antibody immunohistochemistry.  This image was taken for the unmodified form of this product. Other forms have not been tested.
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BCL2L1 / BCL-XL Mouse anti-Human Monoclonal (Ready-to-Use) (BX006) Antibody
Mouse, Dog, Sheep, Bovine, Rat, Hamster, Pig, Horse, Chimpanzee, Human, Monkey
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated, Ready-to-Use
7 ml/$550
BCL2L1 / BCL-XL Antibody - Bcl-X antibody immunohistochemistry.  This image was taken for the unmodified form of this product. Other forms have not been tested.
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BCL2L1 / BCL-XL Mouse anti-Human Monoclonal (Azide-free, BSA-free) (BX006) Antibody
Mouse, Dog, Sheep, Bovine, Rat, Hamster, Pig, Horse, Chimpanzee, Human, Monkey
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated, Azide-free, BSA-free
100 µg/$550
BCL2L1 / BCL-XL Antibody - Immunohistochemical analysis of BCLX (pS62) staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX. w
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BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal (pSer62) Antibody
Mouse, Dog, Sheep, Bovine, Rat, Pig, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$305
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BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$554
BCL2L1 / BCL-XL Antibody - Formalin-fixed, paraffin-embedded human Hodgkin's lymphoma stained with anti-Bcl-X antibody (SPM165).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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BCL2L1 / BCL-XL Mouse anti-Human Monoclonal (aa3-14) (Azide-free, BSA-free) (SPM165) Antibody
Rabbit, Mouse, Dog, Sheep, Bovine, Rat, Hamster, Pig, Horse, Bat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$550
BCL2L1 / BCL-XL Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal (aa46-66) Antibody
Mouse, Dog, Sheep, Bovine, Rat, Gerbil, Human
IHC-Fr, IHC-P, IP, WB
Unconjugated
50 µl/$460
BCL2L1 / BCL-XL Antibody - Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using BCL-XL (Phospho-Thr47) Antibody. The picture on the right is blocked with the phospho peptide.
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BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal (pThr47) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$318; 100 µl/$378
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BCL2L1 / BCL-XL Mouse anti-Human Monoclonal (PE) Antibody
Human
Flo, IHC, IP, WB
PE Conjugated
100 µg/$665
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BCL2L1 / BCL-XL Mouse anti-Human Monoclonal (Biotin) (7B2.5) Antibody
Human
Flo, IHC, IP, WB
Biotin Conjugated
0.1 mg/$445
BCL2L1 / BCL-XL Antibody - Immunohistochemical of paraffin-embedded Human Colon cancer tissue using BCL2L1 Monoclonal Antibody at dilution of 1:200
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BCL2L1 / BCL-XL Mouse anti-Human Monoclonal (aa1-209) (2C11C2) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$306; 100 µg/$376
BCL2L1 / BCL-XL Antibody - Western blot analysis of extracts from Hela cells.
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BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal (pSer62) Antibody
IF, IHC, WB
Unconjugated
50 µl/$306; 100 µl/$381; 200 µl/$489
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BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal (aa46-66) Antibody
Mouse, Dog, Rat, Hamster, Pig, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$471
BCL2L1 / BCL-XL Antibody - Western blot of extracts from HeLa cells (lane 1) and human PBMC (lane 2), using anti-Bcl-X, clone 2H12.
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BCL2L1 / BCL-XL Mouse anti-Human Monoclonal (2H12) Antibody
Mouse, Human
IP, WB
Unconjugated
25 µg/$256; 100 µg/$321
BCL2L1 / BCL-XL Antibody - Bcl-XL was detected in paraffin-embedded sections of human tonsil tissues using rabbit anti- Bcl-XL Antigen Affinity purified polyclonal antibody
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BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal Antibody
Human
Flo, ICC, IHC, IHC-P, WB
Unconjugated
100 µg/$421
BCL2L1 / BCL-XL Antibody - 1:200 staining mouse kidney tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal (pThr47) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µl/$369; 200 µl/$411
BCL2L1 / BCL-XL Antibody - 1:100 staining human liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µl/$369; 200 µl/$411
Select
BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal (aa1-209) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
50 µg/$284; 100 µg/$348
BCL2L1 / BCL-XL Antibody - Immunohistochemical analysis of BCLX (pT47) staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP-conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal (pThr47) Antibody
Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$305
BCL2L1 / BCL-XL Antibody - Immunohistochemical analysis of BCLX staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP-conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal (Internal) Antibody
Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$289
BCL2L1 / BCL-XL Antibody - 1:100 staining human lung carcinoma tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
BCL2L1 / BCL-XL Rabbit anti-Human Polyclonal (pSer62) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µl/$369; 200 µl/$411
BCL2L1 / BCL-XL Antibody - Formalin-fixed, paraffin-embedded human Hodgkin's lymphoma stained with peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of Hodgkin's cells.  This image was taken for the unmodified form of this product. Other forms have not been tested.
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BCL2L1 / BCL-XL Mouse anti-Mouse Monoclonal (Azide-free) (7D9) Antibody
Mouse
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free
0.1 ml/$573; 0.2 ml/$819
BCL2L1 / BCL-XL Antibody - BCL2L1 Antibody western blot of HepG2,MDA-MB-231,mouse NIH/3T3 and rat PC-12 cell line lysates (35 ug/lane). The BCL2L1 antibody detected the BCL2L1 protein (arrow).
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BCL2L1 / BCL-XL Mouse anti-Human Monoclonal (804CT19.1.4) Antibody
Mouse, Rat, Human
WB
Unconjugated
400 µl/$386
Viewing 1-25 of 180 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).