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Anti-BCL10 / BCL-10 Antibody (clone 151, RPE) LS-C188407

Ordering

Wt. Vol. Conc. Price
- 100 tst - $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular BCL10 / BCL-10 Antibodies

Anti-BCL10 / BCL-10 Antibody (aa122-168) LS-C74728
Mouse Monoclonal (IgG1) to Human BCL10 / BCL-10
Human
IHC, Western blot, ELISA
Unconjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 151] (IgG1) to Human BCL10 / BCL-10
Human
IHC - Paraffin, Western blot, Immunoprecipitation, Flow Cytometry, ELISA (applications tested for the base form of this product only)
RPE Conjugated

Details

Human BCL10 / BCL-10
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [151]
R. Phycoerythrin. Also available Unconjugated.
Protein G purified
Unmodified

Applications

  • IHC - Paraffin
  • Western blot
  • Immunoprecipitation
  • Flow Cytometry (1:1)
  • ELISA
  • (applications tested for the base form of this product only)

Specificity and Use

BCL10 / BCL-10 antibody was raised against full length recombinant Bcl-10.
Recognizes human B-cell lymphoma/leukaemia 10 (Bcl-10), a 31kD CARD (caspase recruitment domain) containing molecule that is involved in the regulation of apoptosis. Bcl-10 was originally identified through its direct involvement in t(1;14)(p22;q32) of mucosa-associated lymphoid tissue (MALT) lymphoma. The Bcl-10 molecule is predominantly located in the cytoplasm but expression has also been reported in the nucleus of some lymphomas. Recent reports suggest that Bcl-10 is essential for nuclear factor (NF)-kappaB activation after lymphocyte receptor antigen stimulation and for the development of mature B-cells.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS, 0.09% sodium azide, 1% BSA, 5% sucrose
100 tst Distilled water
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles. Protect from light.
For research use only.

About BCL10 / BCL-10

O95999 NM_003921 NP_003912.1

BCL10 Antibody, Bcl-10 Antibody, B-cell CLL/lymphoma 10 Antibody, B-cell lymphoma/leukemia 10 Antibody, CARMEN Antibody, CARD-like apoptotic protein Antibody, CCARMEN Antibody, C-E10 Antibody, CIPER Antibody, Cellular-E10 Antibody, HCLAP Antibody, Cellular homolog of vCARMEN Antibody, CLAP Antibody, ME10 Antibody

Apoptosis is related to many diseases including cancer. Cell death signals are transduced by death domain (DD) and caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include ARC, RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD containing protein was recently identified by several groups and designated Bcl10, CIPER, mE10, CARMEN, CLAP. Bcl10 is a cellular homolog of the equine herpesvirus-2 E-10 gene.

Immunohistochemistry

Immunohistochemistry
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/8/2016

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