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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Basigin / Emmprin / CD147 Antibody (Biotin) LS‑C14287
CD147 antibody LS-C14287 is a biotin-conjugated rat monoclonal antibody to mouse CD147 (Basigin / Emmprin). Validated for Flow.
Antibody
Catalog
Size
Price
LS-C14287-100
100 µg
$415

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Anti-CD147 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1950 concentration 10 ug/ml.
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Product Description

CD147 antibody LS-C14287 is a biotin-conjugated rat monoclonal antibody to mouse CD147 (Basigin / Emmprin). Validated for Flow.
About Basigin / Emmprin / CD147
Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes. P35613 NM_001728 NP_001719.2

BSG Antibody, 5F7 Antibody, Basigin Antibody, Basigin (Ok blood group) Antibody, CD147 antigen Antibody, Collagenase stimulatory factor Antibody, EMMPRIN Antibody, OK Antibody, OK blood group antigen Antibody, TCSF Antibody, CD147 Antibody, M6 Antibody


Specifications

Target
Mouse Basigin / Emmprin / CD147
Host
Rat
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Biotin
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Flow Cytometry
Immunogen
Fusion protein mCD147dO-2rCD4d3 +4.
Specificity
Recognizes mouse CD147 (also known as basigin). Clone recognizes both isoforms of CD147, the common form containing 2 Ig-like domains and the rare form containing 3 Ig-like domains.
Usage
Suitable for use in Flow Cytometry. Flow Cytometry: Neat, Use 10 ul to label 1E6 cells in 100ul. Membrane permeabilization is required for this application. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, pH 7.4, 0.09% Sodium Azide, 1% BSA
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/20/2018

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