Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
Specificity and Use
BAK1 / BAK antibody was raised against synthetic peptide from N-Terminus of human BAK1 (Q16611, NP_001179). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla (100%); Marmoset (86%); Horse (80%).
Human BAK1 / BAK
Lyophilized from PBS with 2% sucrose
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
BAK1 Antibody, Apoptosis regulator BAK Antibody, BAK Antibody, BCL2L7 Antibody, Bcl-2-like protein 7 Antibody, BCL2-antagonist/killer 1 Antibody, Bcl2-L-7 Antibody, BCL2-like 7 protein Antibody, CDN1 Antibody, Pro-apoptotic protein BAK Antibody, BAK-LIKE Antibody
Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bak, a pro-apoptotic Bcl-2 family member, is an oligomeric protein that localizes to the mitochondria.