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Anti-ATXN3 / JOS Antibody (aa1-245) LS-C186388


Wt. Vol. Conc. Price
- 100 µl 0.73 mg/ml $335

LSBio (Direct) LSBio (Direct)

ATXN3 / JOS Antibody LS-C186388 Images

[click image for a larger image and more details]
IHC of paraffin-embedded H661 xenograft using Ataxin 3 antibody at 1:500 dilution.
Western blot
Sample (50 ug of whole cell lysate).
Western blot
Sample (30 ug of whole cell lysate).

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Rabbit Polyclonal (IgG) to Human ATXN3 / JOS
Human, Mouse
IHC - Paraffin, Western blot


Human ATXN3 / JOS
Human, Mouse (tested or 100% immunogen sequence identity)
Rat, Bovine, Pig (at least 90% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified


IHC - Paraffin (1:100 - 1:1000), Western blot (1:500 - 1:3000)

Specificity and Use

ATXN3 / JOS antibody was raised against recombinant fragment corresponding to a region within amino acids 1 and 245 of Ataxin 3 (SwissProt P54252). Percent identity by BLAST analysis: Human (100%); Pig (99%); Bovine (98%); Rat (96%).
Human ATXN3 / JOS
IHC-paraffin: Suggested antigen retrieval using heat mediated 10 mM Citrate buffer (pH 6.0) or Tris-EDTA buffer (pH 8.0).


0.1 M Tris-glycine, pH 7.0, 20% glycerol, 0.01% Thimerosal
Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
For research use only.

About ATXN3 / JOS

P54252 NM_004993 NP_004984.2

ATXN3 Antibody, ATX3 Antibody, Ataxin 3 Antibody, Ataxin 3 variant h Antibody, AT3 Antibody, Ataxin 3 variant m Antibody, Ataxin 3 variant ref Antibody, Ataxin-3 Antibody, Olivopontocerebellar ataxia 3 Antibody, SCA3 Antibody, MJD1 Antibody, JOS Antibody, Josephin Antibody, MJD Antibody

Deubiquitinating enzyme involved in protein homeostasis maintenance, transcription, cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. Binds long polyubiquitin chains and trims them, while it has weak or no activity against chains of 4 or less ubiquitins.


IHC of paraffin-embedded H661 xenograft using Ataxin 3 antibody at 1:500 dilution.

Western blot

Western blot
Sample (50 ug of whole cell lysate). A: mouse brain. 10% SDS PAGE. ATXN3 / JOS antibody diluted at 1:500.

Western blot

Western blot
Sample (30 ug of whole cell lysate). A: U87-MG. 10% SDS PAGE. ATXN3 / JOS antibody diluted at 1:1000.

Requested From: United States
Date Requested: 10/9/2015

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