Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis.
Immunoperoxidase of monoclonal antibody to ASNA1 on formalin-fixed paraffin-embedded human testis. [antibody concentration 0.5 ug/ml]
Immunofluorescence of monoclonal antibody to ASNA1 on HeLa cell. [antibody concentration 10 ug/ml]
ASNA1 monoclonal antibody (M03), clone 2H3 Western blot of ASNA1 expression in HeLa.
ASNA1 monoclonal antibody (M03), clone 2H3. Western blot of ASNA1 expression in PC-12.
Western blot of ASNA1 expression in transfected 293T cell line by ASNA1 monoclonal antibody (M03), clone 2H3.
Enzyme-Linked Immunosorbent Assay
Detection limit for recombinant GST tagged ASNA1 is approximately 0.03 ng/ml as a capture antibody.
Western blot of ASNA1 over-expressed 293 cell line, cotransfected with ASNA1 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with ASNA1 monoclonal antibody, clone 2H3. GAPDH ( 36.1 kD ) used as specificity.