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Anti-APP / Beta Amyloid Precursor Antibody LS-C42840

Ordering

Wt. Vol. Conc. Price
- 100 µl - $355
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular APP / Beta Amyloid Precursor Antibodies

Anti-APP / Beta Amyloid Precursor Antibody (Thr668) IHC-plus™ LS-B1462
Rabbit Polyclonal (IgG) to Human APP / Beta Amyloid Precursor
Human, Mouse, Rat
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image
Anti-APP / Beta Amyloid Precursor Antibody (aa18-289, clone J4H9) IHC-plus™ LS-B2970
Mouse Monoclonal [clone J4H9] (IgG2b,k) to Human APP / Beta Amyloid Precursor
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-APP / Beta Amyloid Precursor Antibody (C-Terminus) LS-C193927
Rabbit Polyclonal (IgG) to Human APP / Beta Amyloid Precursor
Human, Mouse, Rat
Western blot, Immunoprecipitation
Unconjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human APP / Beta Amyloid Precursor
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated

Details

Human APP / Beta Amyloid Precursor
Rabbit
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Unmodified

Applications

  • IHC - Paraffin
  • Western blot
  • ELISA

Specificity and Use

APP / Beta Amyloid Precursor antibody was raised against disaggregated paired helical filaments.
Neurofibrillary tangles (NFT) are made up of paired helical filaments and are a feature of Alzheimer's disease (AD). AHP564 recognizes NFT and degenerating plaque neurites in cases of AD, Down's Syndrome and normal aged individuals. AHP564 recognizes all NFT as well as paired helical filament-containing neurites.
Immunohistology: This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections.

Packaging

Serum, 0.09% sodium azide.
For research use only.

About APP / Beta Amyloid Precursor

P05067 NM_000484 NP_000475.1

APP Antibody, ABPP Antibody, A4 Antibody, ABETA Antibody, AD1 Antibody, Alzheimer disease Antibody, Amyloid beta Antibody, Beta-amyloid peptide Antibody, APPI Antibody, Beta amyloid Antibody, CVAP Antibody, AAA Antibody, PN2 Antibody, PreA4 Antibody, Amyloid beta A4 protein Antibody, Peptidase nexin-II Antibody, CTFgamma Antibody, PN-II Antibody, Protease nexin-II Antibody

Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP.

Immunohistochemistry

Immunohistochemistry
Staining of formalin-fixed paraffin-embedded Alzheimer's disease brain (hippocampus), showing staining of neurofibrillary tangles and dystrophic neurites in senile plaques using Rabbit anti-Human neurofibrillary tangles polyclonal antibody (LS-C42840).
 

Requested From: United States
Date Requested: 12/3/2016

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