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Anti-APC Antibody (N-Terminus) LS-C69087

Ordering

Wt. Vol. Conc. Price
50 µg - - $485
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular APC Antibodies

Anti-APC Antibody (C-Terminus) IHC-plus™ LS-B2788
Rabbit Polyclonal to Human APC
Human, Mouse, Rat
IHC - Paraffin, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image
Anti-APC Antibody (phospho-Ser2054) LS-C351830
Rabbit Polyclonal to Human APC
Human, Monkey, Mouse, Rat, Pig
Western blot
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG2b) to Human APC
Human, Mouse, Rat
IHC - Paraffin, Immunofluorescence
Unconjugated

Details

Human APC
Mouse
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG2b Monoclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin
  • Immunofluorescence

Specificity and Use

APC antibody was raised against immunogen used was a recombinant amino terminal fragment of APC. Epitope: Epitope is within amino acid residues 1-226 of APC.
N-Terminus
This antibody has been shown to detect oligodendrocytes and astrocytes. Species cross-reactivity: Cross-reacts with Human, Mouse and Rat.
Suitable for use in Immunofluorescence and Immunohistochemistry (paraffin-embedded sections).

Packaging

0.1% sodium azide; 0.2% Gelatin, 0.05 M sodium phosphate.
For research use only.

About APC

P25054 NM_000038 NP_000029.2

APC Antibody, Adenomatosis polyposis coli Antibody, Adenomatous polyposis coli Antibody, BTPS2 Antibody, Deleted in polyposis 2.5 Antibody, DP2 Antibody, DP2.5 Antibody, FPC Antibody, GS Antibody, Protein APC Antibody, PPP1R46 Antibody, DP3 Antibody

Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.

Requested From: United States
Date Requested: 12/7/2016

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