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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ANAPC1 / APC1 Antibody (aa1311‑1360) LS‑C119530
APC1 antibody LS-C119530 is an unconjugated rabbit polyclonal antibody to APC1 (ANAPC1) from human and mouse. Validated for IF and Peptide-ELISA.
Catalog
Size
Price
LS-C119530-50
50 µl
Unavailable
LS-C119530-100
100 µl
Unavailable

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Product Description

APC1 antibody LS-C119530 is an unconjugated rabbit polyclonal antibody to APC1 (ANAPC1) from human and mouse. Validated for IF and Peptide-ELISA.
About ANAPC1 / APC1
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Q9H1A4 NM_022662 NP_073153.1

ANAPC1 Antibody, APC1 Antibody, Cyclosome subunit 1 Antibody, MCPR Antibody, Mitotic checkpoint regulator Antibody, TSG24 Antibody


Specifications

Target
Human ANAPC1 / APC1
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Immunofluorescence (1:100 - 1:500)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:10000)
Immunogen
ANAPC1 / APC1 antibody was raised against synthetic peptide from human ANAPC1 (aa1311-1360).
Epitope
aa1311-1360
Specificity
Cyclosome 1 Antibody detects endogenous levels of total Cyclosome 1 protein.
Presentation
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Storage
Store at -20°C for up to 1 year.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunofluorescence

Immunofluorescence of HepG2 cells, using Cyclosome 1 Antibody. The picture on the right is treated with the synthesized peptide.
Immunofluorescence of HepG2 cells, using Cyclosome 1 Antibody. The picture on the right is treated with the synthesized peptide.

Immunofluorescence

Immunofluorescence of HepG2 cells, using Cyclosome 1 Antibody. The picture on the right is treated with the synthesized peptide.
Immunofluorescence of HepG2 cells, using Cyclosome 1 Antibody. The picture on the right is treated with the synthesized peptide.

Immunofluorescence

Immunofluorescence of HepG2 cells, using Cyclosome 1 Antibody. The picture on the right is treated with the synthesized peptide.
Immunofluorescence of HepG2 cells, using Cyclosome 1 Antibody. The picture on the right is treated with the synthesized peptide.

Immunofluorescence

Immunofluorescence of HepG2 cells, using Cyclosome 1 Antibody. The picture on the right is treated with the synthesized peptide.
Immunofluorescence of HepG2 cells, using Cyclosome 1 Antibody. The picture on the right is treated with the synthesized peptide.


Requested From: 
Date Requested: 6/18/2018

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