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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ALK3 / BMPR1A Antibody (Internal) LS‑C4216
BMPR1A antibody LS-C4216 is an unconjugated rabbit polyclonal antibody to human BMPR1A (ALK3). Validated for IP and WB.
Antibody
Catalog
Size
Price
LS-C4216-100
100 µg (0.25 mg/ml)
$605

Popular ALK3 / BMPR1A Products

IHC of paraffin-embedded colon cancer tissues using BMPR1A mouse monoclonal antibody with DAB staining.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Flow Cytometry, ELISA
Antibody
Species: Human, Mouse
Applications: IHC, Western blot, ELISA
Anti-ALK3 / BMPR1A antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9804 dilution 1:100.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot
Anti-BMPR1A antibody IHC of human pancreas, exocrine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7551 concentration 5 ug/ml.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Anti-ALK3 / BMPR1A antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10363 dilution 1:50.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry, ELISA

Product Description

BMPR1A antibody LS-C4216 is an unconjugated rabbit polyclonal antibody to human BMPR1A (ALK3). Validated for IP and WB.

Specifications

Target
Human ALK3 / BMPR1A
Synonyms
BMPR1A, 10q23del, ALK3, ALK-3, BMP type-1A receptor, BMPR-1A, CD292, CD292 antigen, Activin receptor-like kinase 3, ACVRLK3, SKR5
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1 - 3 µg/ml)
  • Immunoprecipitation
  • (applications tested for the base form of this product only)
Immunogen
ALK3 / BMPR1A antibody was raised against synthetic peptide derived from an internal region of the human BMPR-1A (bone morphogenetic protein receptor type 1A, Serine/threonine protein kinase receptor R5 (SKR5), activin receptor-like kinase-3 (ALK-3)), which differs from mouse and rat BMPR-1A by one non-conservative amino acid replacement.
Epitope
Internal
Specificity
Recognizes human BMPR-1A at ~60 kD. Reactivity has been confirmed with human SK-OV-3, NGP96, SKMEL-19, SK-MEL-37, A375, MeWo cell lysates and mouse ovary homogenates. Based on amino acid sequence homology, reactivity with rat is also expected. Species sequence homology: rat.
Usage
Suitable for use in Western Blot and Immunoprecipitation. Western Blot: 1-3 ug/ml. Immunoprecipitation: 7 ug/reaction.
Presentation
PBS, pH 7.4, 0.09% Sodium Azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About ALK3 / BMPR1A
The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. P36894 NM_004329 NP_004320.2


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Requested From: United States
Date Requested: 10/15/2018

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