Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
This Activin Receptor Type IA (ACVR1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-162 amino acids from the Central region of human Activin Receptor Type IA (ACVR1).
PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
ACVR1 Antibody, Activin A receptor type I Antibody, Activin A receptor, type I Antibody, ACTR-I Antibody, ActRIA Antibody, ACVR1A Antibody, ALK2 Antibody, Activin receptor-like kinase 2 Antibody, Activin receptor type-1 Antibody, ACTRI Antibody, ACVRLK2 Antibody, ALK-2 Antibody, Activin receptor type I Antibody, Actr1 Antibody, FOP Antibody, Hydroxyalkyl-protein kinase Antibody, SKR1 Antibody, TSRI Antibody, TSR-I Antibody, Tsk7L Antibody
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. HC = hepatocarcinoma.
Western blot of lysate from HepG2 cell line, using ACVR1 Antibody (R147). Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.
ACVR1 Antibody (R147) western blot of U937 cell line lysates (35 ug/lane). The ACVR1 antibody detected the ACVR1 protein (arrow).
Western blot of ACVR1 (arrow) using rabbit polyclonal ACVR1 Antibody (R147). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ACVR1 gene.
Requested From: United States
Date Requested: 2/20/2017