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Anti-ADGRE2 / EMR2 Antibody (clone 2A1, Biotin) LS-C188289

Catalog Size Price
LS-C188289-100 100 µg (0.1 mg/ml) Unavailable

Related Products

50 ADGRE2 / EMR2 Antibodies

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Anti-ADGRE2 / EMR2 Antibody (N-Terminus) IHC-plus™ LS-A6306
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Anti-EMR2 antibody LS-A6306 IHC of human lung, neutrophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ADGRE2 / EMR2 Antibody (N-Terminus) IHC-plus™ LS-A6381
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Anti-EMR2 antibody IHC of human Lymph Node, Non-Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ADGRE2 / EMR2 Antibody LS-C123201
Mouse Monoclonal (IgG1) to Human ADGRE2 / EMR2
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IHC, IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry
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Anti-ADGRE2 / EMR2 Antibody (APC) LS-C125335
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Anti-ADGRE2 / EMR2 Antibody (aa347-509, Biotin) LS-C686285
Rabbit Polyclonal (IgG) to Human ADGRE2 / EMR2
Human
IHC, Western blot
Biotin Conjugated
Western blot of ADGRE2 / EMR2 antibody.

100% Guaranteed
Mouse Monoclonal [clone 2A1] (IgG1) to Human ADGRE2 / EMR2
Human
IHC, IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)
Biotin Conjugated

Details

Human ADGRE2 / EMR2
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [2A1]
Biotin. Also available Unconjugated or conjugated with FITC, RPE.
Protein G purified
Unmodified

Applications

  • IHC
  • IHC - Frozen
  • Western blot
  • Immunoprecipitation
  • Flow Cytometry (1:1)
  • (applications tested for the base form of this product only)

Specificity and Use

ADGRE2 / EMR2 antibody was raised against nIH-3T3 cells stably transfected with EMR2 (EGF1-5) cDNA.
Recognizes human EMR2, a member of the epidermal growth factor-seven transmembrane (EGF-TM7) family of proteins, which is closely related to CD97. EMR2, also known as CD312, is predominantly expressed on myeloid dendritic cells, monocytes and tissue macrophages. Various isoforms of EMR2 have been documented. The ligand for the largest isoform of EMR2 has recently been identified as chrondroitin sulphate, which binds to the fourth EGF-like module of EMR2. Clone 2A1 specifically recognizes the stalk region of EMR2.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS, 0.09% sodium azide, 1% BSA
4°C or -20°C, Avoid freeze-thaw cycles.
For research use only.

About ADGRE2 / EMR2

Q9UHX3 NM_013447 NP_038475.2

ADGRE2 Antibody, CD312 antigen Antibody, EMR2 Antibody, EGF-like module receptor 2 Antibody, CD312 Antibody

ADGRE2 / EMR2 is a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains.

Flow Cytometry

Flow cytometry of human peripheral blood monocytes with Mouse anti-Human CD312: Biotin This image was taken for the unconjugated form of this product. Other forms have not been tested.
Flow cytometry of human peripheral blood monocytes with Mouse anti-Human CD312: Biotin This image was taken for the unconjugated form of this product. Other forms have not been tested.

Flow Cytometry

Flow cytometry of human peripheral blood granulocytes with Mouse anti-Human CD312.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Flow cytometry of human peripheral blood granulocytes with Mouse anti-Human CD312. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: 
Date Requested: 5/26/2018

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