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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ADAM17 / TACE Antibody (C‑Terminus) LS‑C18008
TACE antibody LS-C18008 is an unconjugated rabbit polyclonal antibody to TACE (ADAM17) from mouse and rat. Validated for ELISA and WB.
Antibody
Catalog
Size
Price
LS-C18008-50
50 µg (1 mg/ml)
$445
LS-C18008-100
100 µg
$755

Popular ADAM17 / TACE Products

Anti-ADAM17 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B619 concentration 20 ug/ml.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot
Anti-ADAM17 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4426 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA, Proximity Ligation Assay
Immunocytochemistry of TACE in HeLa cells with TACE antibody at 10 µg/ml.
Species: Human, Mouse, Rat
Applications: ICC, Western blot
Anti-ADAM17 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1821 concentration 20 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Western blot analysis of lysates from K562 cells treated with UV 5', using ADAM 17 (Phospho-Thr735) Antibody. The lane on the right is blocked with the phospho peptide.
Species: Human, Mouse, Rat
Applications: Western blot, Peptide Enzyme-Linked Immunosorbent Assay

Product Description

TACE antibody LS-C18008 is an unconjugated rabbit polyclonal antibody to TACE (ADAM17) from mouse and rat. Validated for ELISA and WB.
About ADAM17 / TACE
Tumor-necrosis factor-a is a proinflammatory cytokine and contributes to a variety of inflammatory disease responses and programmed cell death. TNF-a is synthesized as a 26K type II membrane-bound precursor that is cleaved by a convertase to generate secreted 17K mature TNF-a. TNF-a converting enzyme (TACE) protein was recently purified and the human and mouse TACE cDNAs were cloned by several groups separately. P78536 NM_003183 NP_003174.3

ADAM17 Antibody, CD156B Antibody, CD156b antigen Antibody, CSVP Antibody, ADAM 17 Antibody, NISBD Antibody, TNF-alpha converting enzyme Antibody, TNF-alpha convertase Antibody, TNF-alpha-converting enzyme Antibody, Snake venom-like protease Antibody, TACE Antibody


Specifications

Target
Rat ADAM17 / TACE
Host
Rabbit
Reactivity
Rat, Mouse (tested or 100% immunogen sequence identity)
Predicted
Human (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1 - 10 µg/ml)
  • ELISA
Immunogen
ADAM17 / TACE antibody was raised against a 17 aa peptide near the C-terminus of rat TACE (1) conjugated to KLH.
Epitope
C-Terminus
Specificity
The rat peptide sequence is 100% conserved in mouse and 99% in human TACE. No significant sequence homology exists with other proteases. Antibody cross-reactivity in various species is not established.
Usage
Suitable for use in ELISA and Western Blot. Western Blot: 1-10 ug/ml using ECL.
Presentation
PBS, pH 7.4, 0.1% Sodium Azide, 40% Glycerol, 0.1% BSA
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/18/2018

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