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Anti-ADAM17 / TACE Antibody (aa811-824) IHC-plus™ LS-B4437

Note: This antibody replaces LS-C11165
Catalog Size Price
LS-B4437-50 50 µg (0.5 mg/ml) Unavailable

Related Products

70 ADAM17 / TACE Antibodies

Most Popular ADAM17 / TACE Antibodies

Anti-ADAM17 / TACE Antibody (C-Terminus) LS-C263
Rabbit Polyclonal to Human ADAM17 / TACE
Human, Mouse, Rat
ICC, Western blot
Unconjugated
Immunocytochemistry Image
Anti-ADAM17 / TACE Antibody (aa807-823) IHC-plus™ LS-B619
Rabbit Polyclonal to Human ADAM17 / TACE
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated
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Anti-ADAM17 / TACE Antibody (C-Terminus) IHC-plus™ LS-B1821
Rabbit Polyclonal to Human ADAM17 / TACE
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-ADAM17 / TACE Antibody (clone 1F6) IHC-plus™ LS-B4426
Mouse Monoclonal [clone 1F6] (IgG2b,k) to Human ADAM17 / TACE
Human
IHC - Paraffin, Western blot, ELISA, Proximity Ligation Assay
Unconjugated
Immunohistochemistry Image
Anti-ADAM17 / TACE Antibody (phospho-Thr735) LS-C198591
Rabbit Polyclonal (IgG) to Human ADAM17 / TACE
Human, Mouse, Rat
Western blot, ELISA
Unconjugated
Western blot Image

100% Guaranteed
Goat Polyclonal to Human ADAM17 / TACE
Human, Monkey, Bat, Bovine, Chicken
IHC - Paraffin, Western blot, ELISA
Unconjugated

Details

Human ADAM17 / TACE
Goat
Human, Monkey, Bat, Bovine, Chicken (tested or 100% immunogen sequence identity)
Mouse, Rat, Dog, Hamster, Horse, Pig, Xenopus (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (3.75 µg/ml)
  • Western blot (0.1 - 0.3 µg/ml)
  • ELISA (1:128000)

Specificity and Use

ADAM17 / TACE antibody was raised against synthetic peptide LQRQNRVDSKETEC from the C-terminus of human ADAM17 (NP_003174.3). Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Elephant, Bat, Bovine, Turkey, Sparrow, Chicken, Platypus (100%); Gibbon, Mouse, Rat, Hamster, Panda, Dog, Horse, Pig, Opossum, Lizard, Xenopus (93%).
LS-E25330 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B4437. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa811-824
Human ADAM17. This antibody is expected to recognise isoform 1 (represented by NP_003174) and not isoform 2 (represented by NP_068604).

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About ADAM17 / TACE

P78536 NM_003183 NP_003174.3

ADAM17 Antibody, CD156B Antibody, CD156b antigen Antibody, CSVP Antibody, ADAM 17 Antibody, NISBD Antibody, TNF-alpha converting enzyme Antibody, TNF-alpha convertase Antibody, TNF-alpha-converting enzyme Antibody, Snake venom-like protease Antibody, TACE Antibody

Tumor-necrosis factor-a is a proinflammatory cytokine and contributes to a variety of inflammatory disease responses and programmed cell death. TNF-a is synthesized as a 26K type II membrane-bound precursor that is cleaved by a convertase to generate secreted 17K mature TNF-a. TNF-a converting enzyme (TACE) protein was recently purified and the human and mouse TACE cDNAs were cloned by several groups separately.

Immunohistochemistry

Immunohistochemistry
Anti-ADAM17 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4437 concentration 3.75 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-ADAM17 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4437 concentration 3.75 ug/ml.

Western blot

Western blot
HeLa lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.

Requested From: 
Date Requested: 10/20/2017

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