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Anti-ACCN3 / ASIC3 Antibody (aa285-304) LS-C11723

Note: This antibody replaces LS-C63505

Ordering

Wt. Vol. Conc. Price
- 50 µl - $405
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
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Guinea pig Polyclonal (IgG) to Rat ACCN3 / ASIC3
Rat
IHC, ICC
Unconjugated

Details

Rat ACCN3 / ASIC3
Guinea pig
Rat (tested or 100% immunogen sequence identity)
Mouse (at least 90% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified

Applications

IHC (1:50), ICC (1:50)

Specificity and Use

ACCN3 / ASIC3 antibody was raised against synthetic peptide (C-TASLDPDDFDPEPSDPLGSP) residues 285-304 from the extracellular domain of rat ASIC3. Percent identity by BLAST analysis: Rat (100%); Mouse (90%).
aa285-304
Recognizes rat ASIC3.
Suitable for use in Immunohistochemistry and Immunocytochemistry. Immunohistochemistry (perfusion fixed tissue): 1:50. Perfusion: 1) calcium-free Tyrode's solution, 2) paraformaldehyde-picric acid fixative, and 3) 10% sucrose in PBS as cryo-protectant. Desired tissues were dissected and stored overnight in 10% sucrose, PBS. Immunocytochemistry: 1:50. ASIC3 transfected cells and primary neuronal cell cultures.

Packaging

PBS, pH 7.4, 1% BSA, 0.05% sodium azide, 40% glycerol.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About ACCN3 / ASIC3

Q9UHC3 NM_020321 NP_064717.1

ASIC3 Antibody, Acid-sensing ion channel 3 Antibody, Acid-sensing ion channel Antibody, ACCN3 Antibody, HASIC3 Antibody, HTNaC1 Antibody, Modulatory subunit of ASIC2a Antibody, SLNAC1 Antibody, DRASIC Antibody, Testis sodium channel 1 Antibody, TNaC1 Antibody

ACCN3 / ASIC3 is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes.

Requested From: United States
Date Requested: 9/30/2016

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