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ACCN3 / ASIC3 Antibody (aa285‑304) LS‑C11723
Note: This antibody replaces LS-C63505
ASIC3 antibody LS-C11723 is an unconjugated guinea pig polyclonal antibody to rat ASIC3 (ACCN3). Validated for ICC and IHC.
Antibody
Catalog
Size
Price
LS-C11723-50
50 µl
$445

Popular ACCN3 / ASIC3 Products

ACCN3 / ASIC3 antibody LS-C31243 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Rabbit
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Rat, Mouse
Applications: IHC, Western blot
WB of ACCN3 / ASIC3 antibody. Lane 1: Rat Brain Tissue Lysate. Lane 2: Rat Testis Tissue Lysate. Lane 3: U87 Cell Lysate. Lane 4: NEURO Cell Lysate. Lane 5: SMMC Cell Lysate.
Species: Human, Monkey, Mouse, Rat
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Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Antibody
Species: Human
Applications: Western blot, ELISA

Product Description

ASIC3 antibody LS-C11723 is an unconjugated guinea pig polyclonal antibody to rat ASIC3 (ACCN3). Validated for ICC and IHC.

Specifications

Target
Rat ACCN3 / ASIC3
Synonyms
ASIC3, Acid-sensing ion channel 3, Acid-sensing ion channel, ACCN3, HASIC3, HTNaC1, Modulatory subunit of ASIC2a, SLNAC1, DRASIC, Testis sodium channel 1, TNaC1
Host
Guinea pig
Reactivity
Rat (tested or 100% immunogen sequence identity)
Predicted
Mouse (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC (1:50)
  • ICC (1:50)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
ACCN3 / ASIC3 antibody was raised against synthetic peptide (C-TASLDPDDFDPEPSDPLGSP) residues 285-304 from the extracellular domain of rat ASIC3. Percent identity by BLAST analysis: Rat (100%); Mouse (90%).
Epitope
aa285-304
Specificity
Recognizes rat ASIC3.
Usage
Suitable for use in Immunohistochemistry and Immunocytochemistry. Immunohistochemistry (perfusion fixed tissue): 1:50. Perfusion: 1) calcium-free Tyrode's solution, 2) paraformaldehyde-picric acid fixative, and 3) 10% sucrose in PBS as cryo-protectant. Desired tissues were dissected and stored overnight in 10% sucrose, PBS. Immunocytochemistry: 1:50. ASIC3 transfected cells and primary neuronal cell cultures.
Presentation
PBS, pH 7.4, 0.05% Sodium Azide, 40% Glycerol, 1% BSA
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About ACCN3 / ASIC3
ACCN3 / ASIC3 is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. Q9UHC3 NM_020321 NP_064717.1


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Requested From: United States
Date Requested: 10/22/2018

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