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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ABCC2 / MRP2 Antibody (aa1339‑1541) LS‑C16474
Note: This antibody replaces LS-C16471
MRP2 antibody LS-C16474 is an unconjugated mouse monoclonal antibody to MRP2 (ABCC2) from human and rat. Validated for ICC, IHC and WB.
Antibody
Catalog
Size
Price
LS-C16474-125
125 µg
$770
LS-C16474-250
250 µg
$1,215

Popular ABCC2 / MRP2 Products

Antibody
Species: Human
Applications: Immunofluorescence, Western blot, Immunoprecipitation
Immunohistochemistry Image
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human
Applications: IHC, IHC - Paraffin, IHC - Frozen, ICC, Western blot
Antibody
Species: Mouse
Applications: Western blot, ELISA

Product Description

MRP2 antibody LS-C16474 is an unconjugated mouse monoclonal antibody to MRP2 (ABCC2) from human and rat. Validated for ICC, IHC and WB.

Specifications

Target
Rat ABCC2 / MRP2
Synonyms
ABCC2, ABC30, CMOAT1, CMOAT, DJS, Multidrug resistance protein 2, MRP2, CMRP
Host
Mouse
Reactivity
Rat, Human (tested or 100% immunogen sequence identity)
Clonality
IgG2b Monoclonal
Conjugations
Unconjugated
Purification
Tissue culture supernatant
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen
  • ICC (1:20 - 1:50)
  • Western blot (1:20 - 1:50)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
ABCC2 / MRP2 antibody was raised against recombinant C-terminal rat MRP2 (multidrug resistance-associated protein 2; cMOAT) (aa 1339-1541).
Epitope
aa1339-1541
Specificity
Recognizes human and rat MRP2. Does not cross-react with human P-glycoprotein, MDR3 P-glycoprotein, MRP1, MRP3 or MRP5.
Usage
Suitable for use in Immunocytochemistry, Immunohistochemistry, and Western Blot. Immunocytochemistry: 1:20-1:50 on acetone fixed cytospin preparations. Immunohistochemistry (frozen sections): 1:20 dilution on acetone fixed frozen sections followed by incubation with rabbit anti-mouse IgG and a monoclonal mouse APAAP complex. Note: Mouse samples are not suitable for use in IHC. Western Blot: 1:20-1:50. Use anti-mouse-HRP as secondary antibody.
Presentation
Tissue Culture Supernatant, 0.1% Sodium Azide, 0.7% BSA, Serum free
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About ABCC2 / MRP2
ABCC2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Q92887 NM_000392 NP_000383.1


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Requested From: United States
Date Requested: 10/19/2018

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