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ZNF382 is a KRAB domain zinc finger transcription factor (KZNF). KZNFs play critical roles in the regulation of many cellular processes including differentiation, proliferation and apoptosis. The encoded protein inhibits activating protein 1 (AP-1) and nuclear factor kappa-B (NF-kB) signaling and may function as a tumor suppressor in multiple carcinomas. This gene is found in a cluster with other zinc finger protein genes on the long arm of chromosome 19, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene Name: | zinc finger protein 382 |
Family/Subfamily: | Zinc Finger |
Synonyms: | ZNF382, KS1, Zinc finger protein 382 |
Target Sequences: | NM_032825 NP_116214.2 Q96SR6 |
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