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May be involved in transcriptional regulation as a transcriptional repressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.
Gene Name: | zinc finger protein 224 |
Family/Subfamily: | Zinc Finger |
Synonyms: | ZNF224, Bone marrow zinc finger 2, KOX22, Zinc finger protein 224, ZNF255, Zinc finger protein 255, Zinc finger protein KOX22, ZNF27, BMZF-2, BMZF2, Zinc finger protein 233, Zinc finger protein 27, Zinc finger protein ZNF255, Zinc finger 2, bone marrow |
Target Sequences: | NM_013398 Q9NZL3 Q9NZL3 |
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