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ZMAT3 is a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid.
Gene Name: | zinc finger, matrin-type 3 |
Synonyms: | ZMAT3, PAG608, Zinc finger protein WIG-1, WIG-1, WIG-1/PAG608 protein, Zinc finger protein WIG1, WIG1, Zinc finger, matrin type 3, Zinc finger, matrin-type 3, p53 target zinc finger protein, p53-activated gene 608 protein |
Target Sequences: | NM_022470 NP_071915.1 Q9HA38 |
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