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Acts as transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'.
Gene Name: | Zic family member 3 |
Synonyms: | ZIC3, Heterotaxy 1, HTX1, Zic family member 3, Zinc finger protein ZIC 3, ZNF203, HTX, VACTERLX, Zinc finger protein 203 |
Target Sequences: | NM_003413 NP_003404.1 O60481 |
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