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ZFPM1 / FOG1

zinc finger protein, FOG family member 1

Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. May be involved in regulation of some genes in gonads. May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2.

Gene Name: zinc finger protein, FOG family member 1
Family/Subfamily: Zinc Finger
Synonyms: ZFPM1, Friend of GATA protein 1, Friend of GATA-1, FOG1, Friend of GATA 1, FOG, Zinc finger protein ZFPM1, ZFN89A, Zinc finger protein 89A, FOG-1, ZC2HC11A, ZNF89A
Target Sequences: NM_153813 NP_722520.2 Q8IX07

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
ZFPM1 / FOG1 (3)
No (3)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
ZFPM1 / FOG1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
104.7 kDa
20 µg/$215
ZFPM1 / FOG1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
104.7 kDa
100 µg/$710
ZFPM1 / FOG1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Viewing 1-3 of 3 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).