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ZFP57

ZFP57 zinc finger protein

Binds to a 5'-TGCCGC-3' consensus sequence and recognizes the methylated CpG within this element (By similarity). Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation. Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions. Required for the establishment of maternal methylation imprints at SNRPN locus. Acts as a transcriptional repressor in Schwann cells.

Gene Name: ZFP57 zinc finger protein
Family/Subfamily: Zinc Finger
Synonyms: ZFP57, BA145L22, BA145L22.2, C6orf40, TNDM1, Zinc finger protein 698, ZNF698, Zfp-57, Zinc finger protein 57 homolog
Target Sequences: XM_294093

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
ZFP57 (3)
No (3)
His, N-Terminal (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
ZFP57 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
61.2 kDa
100 µg/$494
ZFP57 Protein
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E. coli
His, N-Terminal
61.2 kDa
50 µg/$419
ZFP57 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
61.2 kDa
20 µg/$150
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).